A map of human breast cancer: new players in stromal-immune crosstalk

Kathleen M. McAndrews; Raghu Kalluri

doi:10.15252/embj.2020106368

A map of human breast cancer: new players in stromal-immune crosstalk

Kathleen M. McAndrews, Raghu Kalluri

Cancer Biology

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

Prominent accumulation of mesenchymal cells within tumors has long been appreciated, and recent studies suggest molecular and functional diversity of stromal components. In this issue, Wu et al (2020) employed single-cell RNA sequencing of primary human breast tumors and identified new subsets of stromal mesenchymal cells with distinct transcriptional profiles, tissue localization, and associative immune microenvironments.

Original language	English (US)
Article number	e106368
Journal	EMBO Journal
Volume	39
Issue number	19
DOIs	https://doi.org/10.15252/embj.2020106368
State	Published - Oct 1 2020

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology

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title = "A map of human breast cancer: new players in stromal-immune crosstalk",

abstract = "Prominent accumulation of mesenchymal cells within tumors has long been appreciated, and recent studies suggest molecular and functional diversity of stromal components. In this issue, Wu et al (2020) employed single-cell RNA sequencing of primary human breast tumors and identified new subsets of stromal mesenchymal cells with distinct transcriptional profiles, tissue localization, and associative immune microenvironments.",

author = "McAndrews, {Kathleen M.} and Raghu Kalluri",

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A map of human breast cancer: new players in stromal-immune crosstalk

Abstract

ASJC Scopus subject areas

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