A mild and efficient method for selective cleavage of ketals and acetals using lithium chloride in water - Dimethyl sulfoxide

Pijus Kumar Mandal; Pinak Dutta; Subhas Chandra Roy

doi:10.1016/S0040-4039(97)01689-4

A mild and efficient method for selective cleavage of ketals and acetals using lithium chloride in water - Dimethyl sulfoxide

Pijus Kumar Mandal
, Pinak Dutta
, Subhas Chandra Roy

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

A mild anil efficient neutral aqueous method for selective cleavage of acetals and ketals to the corresponding carbonyl compounds has been established by using LiCI in H₂O-DMSO at elevated temperature. While aryl and α,β-unsaturated ketals and acetals underwent smooth cleavage, diaryl, non-aryl and isolated ketals and acetals remained unaffected under the reaction conditions.

Original language	English (US)
Pages (from-to)	7271-7274
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	41
DOIs	https://doi.org/10.1016/S0040-4039(97)01689-4
State	Published - Oct 13 1997
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(97)01689-4

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title = "A mild and efficient method for selective cleavage of ketals and acetals using lithium chloride in water - Dimethyl sulfoxide",

abstract = "A mild anil efficient neutral aqueous method for selective cleavage of acetals and ketals to the corresponding carbonyl compounds has been established by using LiCI in H2O-DMSO at elevated temperature. While aryl and α,β-unsaturated ketals and acetals underwent smooth cleavage, diaryl, non-aryl and isolated ketals and acetals remained unaffected under the reaction conditions.",

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T1 - A mild and efficient method for selective cleavage of ketals and acetals using lithium chloride in water - Dimethyl sulfoxide

AU - Mandal, Pijus Kumar

AU - Dutta, Pinak

AU - Roy, Subhas Chandra

PY - 1997/10/13

Y1 - 1997/10/13

N2 - A mild anil efficient neutral aqueous method for selective cleavage of acetals and ketals to the corresponding carbonyl compounds has been established by using LiCI in H2O-DMSO at elevated temperature. While aryl and α,β-unsaturated ketals and acetals underwent smooth cleavage, diaryl, non-aryl and isolated ketals and acetals remained unaffected under the reaction conditions.

AB - A mild anil efficient neutral aqueous method for selective cleavage of acetals and ketals to the corresponding carbonyl compounds has been established by using LiCI in H2O-DMSO at elevated temperature. While aryl and α,β-unsaturated ketals and acetals underwent smooth cleavage, diaryl, non-aryl and isolated ketals and acetals remained unaffected under the reaction conditions.

UR - https://www.scopus.com/pages/publications/0030658108

UR - https://www.scopus.com/pages/publications/0030658108#tab=citedBy

U2 - 10.1016/S0040-4039(97)01689-4

DO - 10.1016/S0040-4039(97)01689-4

M3 - Article

AN - SCOPUS:0030658108

SN - 0040-4039

VL - 38

SP - 7271

EP - 7274

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 41

ER -

A mild and efficient method for selective cleavage of ketals and acetals using lithium chloride in water - Dimethyl sulfoxide

Abstract

ASJC Scopus subject areas

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