A Molecular Take on Malignant Rhabdoid Tumors

Ming Tang; Roel G.W. Verhaak

doi:10.1016/j.trecan.2016.04.003

A Molecular Take on Malignant Rhabdoid Tumors

Ming Tang
, Roel G.W. Verhaak

Bioinformatics & Computational Biology

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.

Original language	English (US)
Pages (from-to)	217-218
Number of pages	2
Journal	Trends in Cancer
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/j.trecan.2016.04.003
State	Published - May 1 2016

Keywords

malignant rhabdoid tumors
molecular analysis
pediatric cancer
sequencing

ASJC Scopus subject areas

Oncology
Cancer Research

Access to Document

10.1016/j.trecan.2016.04.003

Cite this

@article{244681562cf54878b7e9c602c424b6b9,

title = "A Molecular Take on Malignant Rhabdoid Tumors",

abstract = "The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.",

keywords = "malignant rhabdoid tumors, molecular analysis, pediatric cancer, sequencing",

author = "Ming Tang and Verhaak, \{Roel G.W.\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = may,

day = "1",

doi = "10.1016/j.trecan.2016.04.003",

language = "English (US)",

volume = "2",

pages = "217--218",

journal = "Trends in Cancer",

issn = "2405-8033",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - A Molecular Take on Malignant Rhabdoid Tumors

AU - Tang, Ming

AU - Verhaak, Roel G.W.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.

AB - The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.

KW - malignant rhabdoid tumors

KW - molecular analysis

KW - pediatric cancer

KW - sequencing

UR - https://www.scopus.com/pages/publications/84968754828

UR - https://www.scopus.com/pages/publications/84968754828#tab=citedBy

U2 - 10.1016/j.trecan.2016.04.003

DO - 10.1016/j.trecan.2016.04.003

M3 - Short survey

C2 - 27672680

AN - SCOPUS:84968754828

SN - 2405-8033

VL - 2

SP - 217

EP - 218

JO - Trends in Cancer

JF - Trends in Cancer

IS - 5

ER -

A Molecular Take on Malignant Rhabdoid Tumors

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this