TY - JOUR
T1 - A multicenter evaluation of near-infrared autofluorescence imaging of parathyroid glands in thyroid and parathyroid surgery
AU - Sehnem, Ludovico
AU - Noureldine, Salem I.
AU - Avci, Seyma
AU - Isiktas, Gizem
AU - Elshamy, Mohammed
AU - Saito, Yoshiyuki
AU - Ahmed, Amr H.A.
AU - Tierney, Hien T.
AU - Trinh, Lily N.
AU - Karcioglu, Amanda Silver
AU - Cheung, Anthony Y.
AU - Otremba, Michael
AU - Krishnamurthy, Vikram
AU - Heiden, Katherine
AU - Jin, Judy
AU - Shin, Joyce
AU - Siperstein, Allan
AU - Zafereo, Mark
AU - Tufano, Ralph P.
AU - Randolph, Gregory W.
AU - Kebebew, Electron
AU - Milas, Mira
AU - Duh, Quan yang
AU - Berber, Eren
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2023/1
Y1 - 2023/1
N2 - Background: The usefulness of incorporating near-infrared autofluorescence into the surgical workflow of endocrine surgeons is unclear. Our aim was to develop a prospective registry and gather expert opinion on appropriate use of this technology. Methods: This was a prospective multicenter collaborative study of patients undergoing thyroidectomy and parathyroidectomy at 7 academic centers. A questionnaire was disseminated among 24 participating surgeons. Results: Overall, 827 thyroidectomy and parathyroidectomy procedures were entered into registry: 42% of surgeons found near-infrared autofluorescence useful in identifying parathyroid glands before they became apparent; 67% correlated near-infrared autofluorescence pattern to normal and abnormal glands; 38% of surgeons used near-infrared autofluorescence, rather than frozen section, to confirm parathyroid tissue; and 87% and 78% of surgeons reported near-infrared autofluorescence did not improve the success rate after parathyroidectomy or the ability to find ectopic glands, respectively. During thyroidectomy, 66% of surgeons routinely used near-infrared autofluorescence to rule out inadvertent parathyroidectomy. However, only 36% and 45% felt near-infrared autofluorescence decreased inadvertent parathyroidectomy rates and improved ability to preserve parathyroid glands during central neck dissections, respectively. Conclusion: This survey study identified areas of greatest potential use for near-infrared autofluorescence, which can form the basis of future objective trials to document the usefulness of this technology.
AB - Background: The usefulness of incorporating near-infrared autofluorescence into the surgical workflow of endocrine surgeons is unclear. Our aim was to develop a prospective registry and gather expert opinion on appropriate use of this technology. Methods: This was a prospective multicenter collaborative study of patients undergoing thyroidectomy and parathyroidectomy at 7 academic centers. A questionnaire was disseminated among 24 participating surgeons. Results: Overall, 827 thyroidectomy and parathyroidectomy procedures were entered into registry: 42% of surgeons found near-infrared autofluorescence useful in identifying parathyroid glands before they became apparent; 67% correlated near-infrared autofluorescence pattern to normal and abnormal glands; 38% of surgeons used near-infrared autofluorescence, rather than frozen section, to confirm parathyroid tissue; and 87% and 78% of surgeons reported near-infrared autofluorescence did not improve the success rate after parathyroidectomy or the ability to find ectopic glands, respectively. During thyroidectomy, 66% of surgeons routinely used near-infrared autofluorescence to rule out inadvertent parathyroidectomy. However, only 36% and 45% felt near-infrared autofluorescence decreased inadvertent parathyroidectomy rates and improved ability to preserve parathyroid glands during central neck dissections, respectively. Conclusion: This survey study identified areas of greatest potential use for near-infrared autofluorescence, which can form the basis of future objective trials to document the usefulness of this technology.
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U2 - 10.1016/j.surg.2022.07.057
DO - 10.1016/j.surg.2022.07.057
M3 - Article
C2 - 36511281
AN - SCOPUS:85141278318
SN - 0039-6060
VL - 173
SP - 132
EP - 137
JO - Surgery (United States)
JF - Surgery (United States)
IS - 1
ER -