A panel of restriction fragment length polymorphisms for chromosomal band 11p13

Vicki Huff; Duane A. Compton; Louise C. Strong; Grady F. Saunders

doi:10.1007/BF00200570

A panel of restriction fragment length polymorphisms for chromosomal band 11p13

Vicki Huff, Duane A. Compton, Louise C. Strong, Grady F. Saunders

Genetics

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18 Scopus citations

Abstract

A panel of seven chromosome 11p13 restriction fragment length polymorphisms (RFLPs) detected by five DNA probes is described. Two alleles were identified for each polymorphism, and Mendelian segregation of alleles was observed. Allele frequencies range from 0.13/0.87 to 0.44/0.56. This panel of 11p13 RFLPs will be useful for linkage studies investigating the role of 11p13 genes in Wilms' tumor, aniridia, and genitourinary anomalies. Additionally, these RFLPs will be important tools for studying tumor-specific 11p13 alterations in Wilms' tumor and other cancers.

Original language	English (US)
Pages (from-to)	253-257
Number of pages	5
Journal	Human genetics
Volume	84
Issue number	3
DOIs	https://doi.org/10.1007/BF00200570
State	Published - Feb 1990

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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10.1007/BF00200570

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title = "A panel of restriction fragment length polymorphisms for chromosomal band 11p13",

abstract = "A panel of seven chromosome 11p13 restriction fragment length polymorphisms (RFLPs) detected by five DNA probes is described. Two alleles were identified for each polymorphism, and Mendelian segregation of alleles was observed. Allele frequencies range from 0.13/0.87 to 0.44/0.56. This panel of 11p13 RFLPs will be useful for linkage studies investigating the role of 11p13 genes in Wilms' tumor, aniridia, and genitourinary anomalies. Additionally, these RFLPs will be important tools for studying tumor-specific 11p13 alterations in Wilms' tumor and other cancers.",

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AU - Huff, Vicki

AU - Compton, Duane A.

AU - Strong, Louise C.

AU - Saunders, Grady F.

PY - 1990/2

Y1 - 1990/2

N2 - A panel of seven chromosome 11p13 restriction fragment length polymorphisms (RFLPs) detected by five DNA probes is described. Two alleles were identified for each polymorphism, and Mendelian segregation of alleles was observed. Allele frequencies range from 0.13/0.87 to 0.44/0.56. This panel of 11p13 RFLPs will be useful for linkage studies investigating the role of 11p13 genes in Wilms' tumor, aniridia, and genitourinary anomalies. Additionally, these RFLPs will be important tools for studying tumor-specific 11p13 alterations in Wilms' tumor and other cancers.

AB - A panel of seven chromosome 11p13 restriction fragment length polymorphisms (RFLPs) detected by five DNA probes is described. Two alleles were identified for each polymorphism, and Mendelian segregation of alleles was observed. Allele frequencies range from 0.13/0.87 to 0.44/0.56. This panel of 11p13 RFLPs will be useful for linkage studies investigating the role of 11p13 genes in Wilms' tumor, aniridia, and genitourinary anomalies. Additionally, these RFLPs will be important tools for studying tumor-specific 11p13 alterations in Wilms' tumor and other cancers.

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A panel of restriction fragment length polymorphisms for chromosomal band 11p13

Abstract

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