A primer on the current state-of-the-science neoadjuvant and adjuvant therapy for patients with locally advanced rectal adenocarcinomas

Jeffrey T. Yorio, Nishin A. Bhadkamkar, Bryan K. Kee, Christopher R. Garrett

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Patients with rectal cancers, due to the unique location of the tumor, have a recurrence pattern distinct from colon cancers. Advances in adjuvant therapy over the last three decades have played an important role in improving patient outcomes. This article serves to review the clinical studies that lay the basis for our current standard-of-care treatment of patients with locally advanced rectal cancer, as well as touch upon future ongoing experimental clinical trials of adjuvant chemoradiation therapy.

Original languageEnglish (US)
Article number863034
JournalInternational Journal of Surgical Oncology
Volume2012
DOIs
StatePublished - Sep 18 2012

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Neoadjuvant Therapy
Adenocarcinoma
Rectal Neoplasms
Standard of Care
Colonic Neoplasms
Therapeutics
Clinical Trials
Recurrence
Neoplasms

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

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abstract = "Patients with rectal cancers, due to the unique location of the tumor, have a recurrence pattern distinct from colon cancers. Advances in adjuvant therapy over the last three decades have played an important role in improving patient outcomes. This article serves to review the clinical studies that lay the basis for our current standard-of-care treatment of patients with locally advanced rectal cancer, as well as touch upon future ongoing experimental clinical trials of adjuvant chemoradiation therapy.",
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AU - Garrett, Christopher R.

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