TY - JOUR
T1 - A proposal for the performance, classification, and reporting of lymph node fine-needle aspiration cytopathology
T2 - The Sydney system
AU - Al-Abbadi, Mousa A.
AU - Barroca, Helena
AU - Bode-Lesniewska, Beata
AU - Calaminici, Maria
AU - Caraway, Nancy P.
AU - Chhieng, David F.
AU - Cozzolino, Immacolata
AU - Ehinger, Mats
AU - Field, Andrew S.
AU - Geddie, William R.
AU - Katz, Ruth L.
AU - Lin, Oscar
AU - Medeiros, L. Jeffrey
AU - Monaco, Sara E.
AU - Rajwanshi, Arvind
AU - Schmitt, Fernando C.
AU - Vielh, Philippe
AU - Zeppa, Pio
N1 - Publisher Copyright:
© 2020 S. Karger AG, Basel.
PY - 2020
Y1 - 2020
N2 - Background: The evaluation of lymph nodes (LN) by fineneedle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. Methods: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. It is based on a review of the international literature and on the expertise of the members. The system integrates clinical and imaging data with cytopathological features and ancillary techniques. The project has received the endorsement and patronage of the International Academy of Cytology and the European Federation of the Cytology Societies. Results: Clinical, imaging, and serological data of lymphadenopathies, indications for LN-FNAC, technical procedures, and ancillary techniques are evaluated with specific recommendations. The reporting system includes two diagnostic levels. The first should provide basic diagnostic information and includes five categories: inadequate/insufficient, benign, atypical lymphoid cells of undetermined/uncertain significance, suspicious, and malignant. For each category, specific recommendations are provided. The second diagnostic level, when achievable, should produce the identification of specific benign or malignant entities and additional information by utilizing ancillary testing. Conclusion: The authors believe that the introduction of this system for performing and reporting LN-FNAC may improve the quality of the procedure, the report, and the communication between cytopathologists and the clinicians. This system may lead to a greater acceptance and utilization of LN-FNAC and to a better interdisciplinary understanding of the results of this procedure.
AB - Background: The evaluation of lymph nodes (LN) by fineneedle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. Methods: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. It is based on a review of the international literature and on the expertise of the members. The system integrates clinical and imaging data with cytopathological features and ancillary techniques. The project has received the endorsement and patronage of the International Academy of Cytology and the European Federation of the Cytology Societies. Results: Clinical, imaging, and serological data of lymphadenopathies, indications for LN-FNAC, technical procedures, and ancillary techniques are evaluated with specific recommendations. The reporting system includes two diagnostic levels. The first should provide basic diagnostic information and includes five categories: inadequate/insufficient, benign, atypical lymphoid cells of undetermined/uncertain significance, suspicious, and malignant. For each category, specific recommendations are provided. The second diagnostic level, when achievable, should produce the identification of specific benign or malignant entities and additional information by utilizing ancillary testing. Conclusion: The authors believe that the introduction of this system for performing and reporting LN-FNAC may improve the quality of the procedure, the report, and the communication between cytopathologists and the clinicians. This system may lead to a greater acceptance and utilization of LN-FNAC and to a better interdisciplinary understanding of the results of this procedure.
KW - Fine-needle aspiration cytology
KW - Lymph node
KW - Reporting system
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U2 - 10.1159/000506497
DO - 10.1159/000506497
M3 - Review article
C2 - 32454496
AN - SCOPUS:85088203711
SN - 0001-5547
VL - 64
SP - 306
EP - 322
JO - Acta Cytologica
JF - Acta Cytologica
IS - 4
ER -