TY - JOUR
T1 - A prospective in silico analysis of interdisciplinary and interobserver spatial variability in post-operative target delineation of high-risk oral cavity cancers
T2 - Does physician specialty matter?
AU - Ng, Sweet Ping
AU - Dyer, Brandon A.
AU - Kalpathy-Cramer, Jayashree
AU - Mohamed, Abdallah Sherif Radwan
AU - Awan, Musaddiq J.
AU - Gunn, G. Brandon
AU - Phan, Jack
AU - Zafereo, Mark
AU - Debnam, J. Matthew
AU - Lewis, Carol M.
AU - Colen, Rivka R.
AU - Kupferman, Michael E.
AU - Guha-Thakurta, Nandita
AU - Canahuate, Guadalupe
AU - Marai, G. Elisabeta
AU - Vock, David
AU - Hamilton, Bronwyn
AU - Holland, John
AU - Cardenas, Carlos E.
AU - Lai, Stephen
AU - Rosenthal, David
AU - Fuller, Clifton David
N1 - Publisher Copyright:
© 2018
PY - 2018/8
Y1 - 2018/8
N2 - Background: The aim of this study was to determine the interdisciplinary agreement in identifying the post-operative tumor bed. Methods: Three radiation oncologists (ROs), four surgeons, and three radiologists segmented post-operative tumor and nodal beds for three patients with oral cavity cancer. Specialty cohort composite contours were created by STAPLE algorithm implementation results for interspecialty comparison. Dice similarity coefficient and Hausdorff distance were utilized to compare spatial differentials between specialties. Results: There were significant differences between disciplines in target delineation. There was unacceptable variation in Dice similarity coefficient for each observer and discipline when compared to the STAPLE contours. Within surgery and radiology disciplines, there was good consistency in volumes. ROs and radiologists have similar Dice similarity coefficient scores compared to surgeons. Conclusion: There were significant interdisciplinary differences in perceptions of tissue-at-risk. Better communication and explicit description of at-risk areas between disciplines is required to ensure high-risk areas are adequately targeted.
AB - Background: The aim of this study was to determine the interdisciplinary agreement in identifying the post-operative tumor bed. Methods: Three radiation oncologists (ROs), four surgeons, and three radiologists segmented post-operative tumor and nodal beds for three patients with oral cavity cancer. Specialty cohort composite contours were created by STAPLE algorithm implementation results for interspecialty comparison. Dice similarity coefficient and Hausdorff distance were utilized to compare spatial differentials between specialties. Results: There were significant differences between disciplines in target delineation. There was unacceptable variation in Dice similarity coefficient for each observer and discipline when compared to the STAPLE contours. Within surgery and radiology disciplines, there was good consistency in volumes. ROs and radiologists have similar Dice similarity coefficient scores compared to surgeons. Conclusion: There were significant interdisciplinary differences in perceptions of tissue-at-risk. Better communication and explicit description of at-risk areas between disciplines is required to ensure high-risk areas are adequately targeted.
KW - Interdisciplinary
KW - Interobserver
KW - Oral cavity cancer
KW - Post-operative
KW - Target delineation
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U2 - 10.1016/j.ctro.2018.07.006
DO - 10.1016/j.ctro.2018.07.006
M3 - Article
C2 - 30148217
AN - SCOPUS:85063051940
SN - 2405-6308
VL - 12
SP - 40
EP - 46
JO - Clinical and Translational Radiation Oncology
JF - Clinical and Translational Radiation Oncology
ER -