A protein restriction-dependent sulfur code for longevity

Hong Seok Shim; Valter D. Longo

doi:10.1016/j.cell.2014.12.027

A protein restriction-dependent sulfur code for longevity

Hong Seok Shim, Valter D. Longo

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

The restriction of proteins has recently emerged as the most important factor for the beneficial effects of calorie restriction. Hine et al. now provide strong evidence for the role of the hydrogen sulfide (H₂S) gas in the protective effects of calorie and protein restriction against ischemia/reperfusion injury (IRI) but also implicate H₂S in longevity extension in model organisms.

Original language	English (US)
Pages (from-to)	15-17
Number of pages	3
Journal	Cell
Volume	160
Issue number	1-2
DOIs	https://doi.org/10.1016/j.cell.2014.12.027
State	Published - Jan 15 2015
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2014.12.027

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title = "A protein restriction-dependent sulfur code for longevity",

abstract = "The restriction of proteins has recently emerged as the most important factor for the beneficial effects of calorie restriction. Hine et al. now provide strong evidence for the role of the hydrogen sulfide (H2S) gas in the protective effects of calorie and protein restriction against ischemia/reperfusion injury (IRI) but also implicate H2S in longevity extension in model organisms.",

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AB - The restriction of proteins has recently emerged as the most important factor for the beneficial effects of calorie restriction. Hine et al. now provide strong evidence for the role of the hydrogen sulfide (H2S) gas in the protective effects of calorie and protein restriction against ischemia/reperfusion injury (IRI) but also implicate H2S in longevity extension in model organisms.

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A protein restriction-dependent sulfur code for longevity

Abstract

ASJC Scopus subject areas

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