Abstract
OBJECTIVE. Imaging plays an important role in the diagnosis and staging of malignancies. Many common lymphoproliferative and other solid tumor malignancies can be viral-related. CONCLUSION. This review discusses the imaging findings that can be associated with common viral-induced malignancies. Knowledge of these imaging presentations can help narrow the differential diagnosis to reach a specific diagnosis through a precise workup and proper management.
Original language | English (US) |
---|---|
Pages (from-to) | W1-W10 |
Journal | American Journal of Roentgenology |
Volume | 214 |
Issue number | 1 |
DOIs | |
State | Published - 2020 |
Keywords
- Cancer
- Oncogenic viruses
- Radiologic-pathologic correlation
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Fingerprint
Dive into the research topics of 'A review of viral-related malignancies and the associated imaging findings'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS
In: American Journal of Roentgenology, Vol. 214, No. 1, 2020, p. W1-W10.
Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - A review of viral-related malignancies and the associated imaging findings
AU - Consul, Nikita
AU - Menias, Christine O.
AU - Lubner, Meghan G.
AU - Katabathina, Venkata S.
AU - Chahinian, Rita A.
AU - Mansour, Joseph
AU - Elsayes, Khaled M.
N1 - Funding Information: virus and Burkitt lymphoma. Chin J Cancer 2014; 33:609–619 3. Johnson SA, Kumar A, Matasar MJ, Schöder H, Rademaker J. Imaging for staging and response assessment in lymphoma. Radiology 2015; 276:323–338 4. Cheson BD, Fisher RI, Barrington SF, et al.; Alli-ance, Australasian Leukaemia and Lymphoma Group; Eastern Cooperative Oncology Group; Eu-ropean Mantle Cell Lymphoma Consortium; Ital-ian Lymphoma Foundation; European Organisa-tion for Research; Treatment of Cancer/Dutch Hemato-Oncology Group; Grupo Español de Médula Ósea; German High-Grade Lymphoma Study Group; German Hodgkin’s Study Group; Japanese Lymphoma Study Group; Lymphoma Study Association; NCIC Clinical Trials Group; Nordic Lymphoma Study Group; Southwest On-cology Group; United Kingdom National Cancer Research Institute. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Luga-no classification. J Clin Oncol 2014; 32:3059–3068 5. Toma P, Granata C, Rossi A, Garaventa A. Multi-modality imaging of Hodgkin disease and non-Hodgkin lymphomas in children. RadioGraphics 2007; 27:1335–1354 6. Liu TY, Wu SJ, Huang MH, et al. EBV-positive Hodgkin lymphoma is associated with suppres-sion of p21cip1/waf1 and a worse prognosis. Mol Cancer 2010; 9:32 7. Flavell KJ, Murray PG. Hodgkin’s disease and the Epstein-Barr virus. Mol Pathol 2000; 53:262–269 8. Mesri EA, Feitelson MA, Munger K. Human viral oncogenesis: a cancer hallmarks analysis. Cell Host Microbe 2014; 15:266–282 9. Guermazi A, Brice P, de Kerviler EE, et al. Extra-nodal Hodgkin disease: spectrum of disease. RadioGraphics 2001; 21:161–179 10. Fahy AS, Kong I, Weitzman S, Dix D, Baruchel S, Gerstle JT. A role for surgery in the treatment of relapsed Hodgkin lymphoma. Pediatr Blood Can-cer 2019; 66:e27402 11. Katabathina VS, Menias CO, Tammisetti VS, et al. Malignancy after solid organ transplantation: comprehensive imaging review. RadioGraphics 2016; 36:1390–1407 12. Dierickx D, Tousseyn T, Gheysens O. How I treat posttransplant lymphoproliferative disorders. Blood 2015; 126:2274–2283 13. Camacho JC, Moreno CC, Harri PA, Aguirre DA, Torres WE, Mittal PK. Posttransplantation lym-phoproliferative disease: proposed imaging clas-sification. RadioGraphics 2014; 34:2025–2038 14. Taylor AL, Marcus R, Bradley JA. Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. Crit Rev Oncol Hematol 2005; 56:155–167 15. Borhani AA, Hosseinzadeh K, Almusa O, Furlan A, Nalesnik M. Imaging of posttransplantation lymphoproliferative disorder after solid organ transplantation. RadioGraphics 2009; 29:981– 1000, discussion, 1000–1002 16. Preiksaitis JK, Keay S. Diagnosis and manage-ment of posttransplant lymphoproliferative disor-der in solid-organ transplant recipients. Clin In-fect Dis 2001; 33(Suppl 1):S38–S46 17. McEvoy SH, McCarthy CJ, Lavelle LP, et al. He-patocellular carcinoma: illustrated guide to sys-tematic radiologic diagnosis and staging accord-ing to guidelines of the American Association for the Study of Liver Diseases. RadioGraphics 2013; 33:1653–1668 [Erratum in RadioGraphics 2014; 34:15A] 18. Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of small hepato-cellular carcinomas in patients with cirrhosis. N Engl J Med 1996; 334:693–699 19. Luo GG, Ou JH. Oncogenic viruses and cancer. Virol Sin 2015; 30:83–84 20. Palladini A, Landuzzi L, Lollini PL, Nanni P. Cancer immunoprevention: from mice to early clinical trials. BMC Immunol 2018; 19:16 21. Lewin M, Gelu-Simeon M, Ostos M, et al. Imag-ing features and prognosis of hepatocellular carci-noma in patients with cirrhosis who are coinfect-ed with human immunodeficiency virus and hepatitis C virus. Radiology 2015; 277:443–453 22. Lewis S, Roayaie S, Ward SC, Shyknevsky I, Jibara G, Taouli B. Hepatocellular carcinoma in chronic hepatitis C in the absence of advanced fibrosis or cirrhosis. AJR 2013; 200:[web]W610–W616 23. Roberts LR, Sirlin CB, Zaiem F, et al. Imaging for the diagnosis of hepatocellular carcinoma: a sys-tematic review and meta-analysis. Hepatology 2018; 67:401–421 24. Iannaccone R, Piacentini F, Murakami T, et al. Hepatocellular carcinoma in patients with nonal-coholic fatty liver disease: helical CT and MR imaging findings with clinical-pathologic com-parison. Radiology 2007; 243:422–430 25. Thompson SM, Garg I, Ehman EC, et al. Non-al-coholic fatty liver disease-associated hepatocel-lular carcinoma: effect of hepatic steatosis on ma-jor hepatocellular carcinoma features at MRI. Br J Radiol 2018; 91:20180345 26. Silva MA, Hegab B, Hyde C, Guo B, Buckels JAC, Mirza DF. Needle track seeding following biopsy of liver lesions in the diagnosis of hepatocellular cancer: a systematic review and meta-analysis. Gut 2008; 57:1592–1596 27. Chernyak V, Fowler KJ, Kamaya A, et al. Liver Imaging Reporting and Data System (LI-RADS) version 2018: imaging of hepatocellular carcinoma in at-risk patients. Radiology 2018; 289:816–830 28. Sneag DB, Krajewski K, Giardino A, et al. Extra- hepatic spread of hepatocellular carcinoma: spec-trum of imaging findings. AJR 2011; 197:[web] W658–W664 29. Zhu Y, Ramos da Silva S, He M, et al. An onco-genic virus promotes cell survival and cellular transformation by suppressing glycolysis. PLoS Pathog 2016; 12:e1005648 30. Restrepo CS, Martínez S, Lemos JA, et al. Imag-ing manifestations of Kaposi sarcoma. RadioGraphics 2006; 26:1169–1185 31. Mudau A, Makhanya NZ, Suleman FE. Dissemi-nated Kaposi sarcoma presenting in unusual loca-tions: a case report. S Afr J Rad 2017; 21:a1260 32. Restrepo CS, Ocazionez D. Kaposi’s sarcoma: im-aging overview. Semin Ultrasound CT MR 2011; 32:456–469 33. Burns J, Shaknovich R, Lau J, Haramati LB. On-cogenic viruses in AIDS: mechanisms of disease and intrathoracic manifestations. AJR 2007; 189:1082–1087 34. Nasti G, Talamini R, Antinori A, et al. AIDS-re-lated Kaposi’s sarcoma: evaluation of potential new prognostic factors and assessment of the AIDS Clinical Trial Group staging system in the HAART era—the Italian Cooperative Group on AIDS and Tumors and the Italian Cohort of Pa-tients Naive From Antiretrovirals. J Clin Oncol 2003; 21:2876–2882 35. Okuku F, Krantz EM, Kafeero J, et al. Evaluation of a predictive staging model for HIV-associated Kaposi sarcoma in Uganda. J Acquir Immune Defic Syndr 2017; 74:548–554 36. Parkin DM, Bray F. Chapter 2: the burden of HPV-related cancers. Vaccine 2006; 24(Suppl 3):S3, 11–25 37. Kobayashi K, Hisamatsu K, Suzui N, Hara A, To-mita H, Miyazaki T. A review of HPV-related head and neck cancer. J Clin Med 2018; 7:241 38. Leijenaar RT, Bogowicz M, Jochems A, et al. De-velopment and validation of a radiomic signature to predict HPV (p16) status from standard CT im-aging: a multicenter study. Br J Radiol 2018; 91:20170498 39. Cantrell SC, Peck BW, Li G, Wei Q, Sturgis EM, Ginsberg LE. Differences in imaging characteris-tics of HPV-positive and HPV-negative oropha-ryngeal cancers: a blinded matched-pair analysis. AJNR 2013; 34:2005–2009 40. Trotta BM, Pease CS, Rasamny JJ, Raghavan P, Mukherjee S. Oral cavity and oropharyngeal squamous cell cancer: key imaging findings for staging and treatment planning. RadioGraphics 2011; 31:339–354 41. Glastonbury CM, Mukherji SK, O’Sullivan B, Lydiatt WM. Setting the stage for 2018: how the changes in the American Joint Committee on Cancer/Union for International Cancer Control Cancer Staging Manual eighth edition impact ra- Publisher Copyright: © American Roentgen Ray Society
PY - 2020
Y1 - 2020
N2 - OBJECTIVE. Imaging plays an important role in the diagnosis and staging of malignancies. Many common lymphoproliferative and other solid tumor malignancies can be viral-related. CONCLUSION. This review discusses the imaging findings that can be associated with common viral-induced malignancies. Knowledge of these imaging presentations can help narrow the differential diagnosis to reach a specific diagnosis through a precise workup and proper management.
AB - OBJECTIVE. Imaging plays an important role in the diagnosis and staging of malignancies. Many common lymphoproliferative and other solid tumor malignancies can be viral-related. CONCLUSION. This review discusses the imaging findings that can be associated with common viral-induced malignancies. Knowledge of these imaging presentations can help narrow the differential diagnosis to reach a specific diagnosis through a precise workup and proper management.
KW - Cancer
KW - Oncogenic viruses
KW - Radiologic-pathologic correlation
UR - http://www.scopus.com/inward/record.url?scp=85077016537&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85077016537&partnerID=8YFLogxK
U2 - 10.2214/AJR.19.21357
DO - 10.2214/AJR.19.21357
M3 - Review article
C2 - 31593515
AN - SCOPUS:85077016537
SN - 0361-803X
VL - 214
SP - W1-W10
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 1
ER -