Abstract
The lack of effective therapeutic agents specifically tailored for chronic pancreatitis (CP) has hampered clinical care and negatively impacted patients' lives. New mechanistic insights now point to novel therapies, which involve both recently developed and/or repurposed agents. This working group focused on 2 main outcomes for CP: Pain and progression of disease. The goal is to frame the essential aspects of trial design including patient-centered outcomes, proposed methods to measure the outcomes of pain and progression, and study design considerations for future trials to facilitate rapid drug development for patients with CP.
Original language | English (US) |
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Pages (from-to) | 1200-1207 |
Number of pages | 8 |
Journal | Pancreas |
Volume | 47 |
Issue number | 10 |
DOIs | |
State | Published - Nov 1 2018 |
Keywords
- chronic pancreatitis
- clinical trial design
- natural history of chronic pancreatitis
- pain in chronic pancreatitis
ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
- Hepatology
- Endocrinology