TY - JOUR
T1 - Acinetobacter calcoaceticus septicemia in patients with cancer
AU - Rolston, Kenneth
AU - Guan, Z.
AU - Bodey, Gerald P.
AU - Elting, Linda
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1985/6
Y1 - 1985/6
N2 - At our institution, 95 cases of Acinetobacter septicemia occurred over a ten-year period (1973 to 1982) in patients being treated for cancer. In 24 patients the infection was polymicrobial, while Acinetobacter ssp was the only offending pathogen in 71 patients. In 76 patients (80%), the infection was related to an indwelling central venous catheter (CVC). A sharp increase in the frequency of Acinetobacter septicemia was noticed in the years 1981 and 1982 and coincided with a marked increase in the number of indwelling CVCs in use. Acute leukemia and breast cancer were the malignancies most commonly associated with Acinetobacter septicemia. The isolates of Acinetobacter calcoaceticus from the patients in this study were highly susceptible to the aminoglycosides and moderately susceptible to trimethoprim-sulfamethoxazole (TMP-SMX), carbenicillin, and tetracycline. Seventy-nine patients recovered frpm their infection with removal of the CVC and antimicrobial chemotherapy. Acinetobacter sp was the cause of death in none of the 16 patients who died. A calcoaceticus is an important nosocomial pathogen causing infections predominantly in immune compromised patients and frequently associated with indwelling catheters.
AB - At our institution, 95 cases of Acinetobacter septicemia occurred over a ten-year period (1973 to 1982) in patients being treated for cancer. In 24 patients the infection was polymicrobial, while Acinetobacter ssp was the only offending pathogen in 71 patients. In 76 patients (80%), the infection was related to an indwelling central venous catheter (CVC). A sharp increase in the frequency of Acinetobacter septicemia was noticed in the years 1981 and 1982 and coincided with a marked increase in the number of indwelling CVCs in use. Acute leukemia and breast cancer were the malignancies most commonly associated with Acinetobacter septicemia. The isolates of Acinetobacter calcoaceticus from the patients in this study were highly susceptible to the aminoglycosides and moderately susceptible to trimethoprim-sulfamethoxazole (TMP-SMX), carbenicillin, and tetracycline. Seventy-nine patients recovered frpm their infection with removal of the CVC and antimicrobial chemotherapy. Acinetobacter sp was the cause of death in none of the 16 patients who died. A calcoaceticus is an important nosocomial pathogen causing infections predominantly in immune compromised patients and frequently associated with indwelling catheters.
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U2 - 10.1097/00007611-198506000-00007
DO - 10.1097/00007611-198506000-00007
M3 - Article
C2 - 4001997
AN - SCOPUS:0021815861
SN - 0038-4348
VL - 78
SP - 647
EP - 651
JO - Southern Medical Journal
JF - Southern Medical Journal
IS - 6
ER -