TY - JOUR
T1 - Acquisition parameters for oncologic imaging with a new SPECT/multislice CT scanner
AU - Núñez, Rodolfo
AU - Erwin, William D.
AU - Wendt, Richard E.
AU - Stachowiak, Anne
AU - Mar, Martha
AU - Stevens, Donna
AU - Madewell, John E.
AU - Yeung, Henry W.
AU - Macapinlac, Homer A.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/4
Y1 - 2010/4
N2 - Introduction: Single photon emission computed tomography/computed tomography (SPECT/CT) delivers in a single imaging modality the functional-metabolic information from the SPECT image, combined with the detailed anatomical information from a diagnostic quality CT scanner. Method: In this review, we provide the details for the acquisition, processing, and display of the SPECT, as well as the CT, and the fused SPECT/CT images, with one of the newest devices that combines a dual-headed gamma camera with a multislice CT scanner. Also, we go over the performance characteristics, including the planning and installation requirements for this type of scanners. In addition, we describe what are the current and feasible near-future applications of this new and exciting hybrid imaging modality. Discussion: The ability to combine an optimized state-of-the-art SPECT image, with resolutions down to 5 mm, with a diagnostic quality CT image - using slices as thin as 1.25 mm - provides a diagnostic advantage that potentially can deliver a more convenient and faster diagnosis, with clinical implications in a significant percentage of patients. This imaging technique has been investigated in a wide range of studies for the oncologic patient, including but not limited to bone scintigraphy, 111In-pentetreotide scintigraphy, lymphoscintigraphy, 67Ga and labeled leukocyte infection imaging, 131I- metaiodobenzylguanidine, parathyroid scintigraphy, 131I diagnostic scintigraphy, and 111In ProstaScint, and for planning of radionuclide therapy. Conclusion: Therefore, this evolving and exciting imaging modality will continue to grow and define its place as an integral part of the evaluation of the cancer patient.
AB - Introduction: Single photon emission computed tomography/computed tomography (SPECT/CT) delivers in a single imaging modality the functional-metabolic information from the SPECT image, combined with the detailed anatomical information from a diagnostic quality CT scanner. Method: In this review, we provide the details for the acquisition, processing, and display of the SPECT, as well as the CT, and the fused SPECT/CT images, with one of the newest devices that combines a dual-headed gamma camera with a multislice CT scanner. Also, we go over the performance characteristics, including the planning and installation requirements for this type of scanners. In addition, we describe what are the current and feasible near-future applications of this new and exciting hybrid imaging modality. Discussion: The ability to combine an optimized state-of-the-art SPECT image, with resolutions down to 5 mm, with a diagnostic quality CT image - using slices as thin as 1.25 mm - provides a diagnostic advantage that potentially can deliver a more convenient and faster diagnosis, with clinical implications in a significant percentage of patients. This imaging technique has been investigated in a wide range of studies for the oncologic patient, including but not limited to bone scintigraphy, 111In-pentetreotide scintigraphy, lymphoscintigraphy, 67Ga and labeled leukocyte infection imaging, 131I- metaiodobenzylguanidine, parathyroid scintigraphy, 131I diagnostic scintigraphy, and 111In ProstaScint, and for planning of radionuclide therapy. Conclusion: Therefore, this evolving and exciting imaging modality will continue to grow and define its place as an integral part of the evaluation of the cancer patient.
KW - Acquisition parameters
KW - Oncologic imaging
KW - SPECT/multislice CT scanner
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U2 - 10.1007/s11307-009-0266-4
DO - 10.1007/s11307-009-0266-4
M3 - Review article
C2 - 20049543
AN - SCOPUS:77953542141
SN - 1536-1632
VL - 12
SP - 110
EP - 138
JO - Molecular Imaging and Biology
JF - Molecular Imaging and Biology
IS - 2
ER -