TY - JOUR
T1 - Adult Primary Brain Neoplasm, Including 2016 World Health Organization Classification
AU - Wang, Kevin Yuqi
AU - Chen, Melissa M.
AU - Malayil Lincoln, Christie M.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - In 2016, the World Health Organization (WHO) central nervous system (CNS) classification scheme incorporated molecular parameters in addition to traditional microscopic features for the first time. Molecular markers add a level of objectivity that was previously missing for tumor categories heavily dependent on microscopic observation for pathologic diagnosis. This article provides a brief discussion of the major 2016 updates to the WHO CNS classification scheme and reviews typical MR imaging findings of adult primary CNS neoplasms, including diffuse infiltrating gliomas, ependymal tumors, neuronal/glioneuronal tumors, pineal gland tumors, meningiomas, nerve sheath tumors, solitary fibrous tumors, and lymphoma.
AB - In 2016, the World Health Organization (WHO) central nervous system (CNS) classification scheme incorporated molecular parameters in addition to traditional microscopic features for the first time. Molecular markers add a level of objectivity that was previously missing for tumor categories heavily dependent on microscopic observation for pathologic diagnosis. This article provides a brief discussion of the major 2016 updates to the WHO CNS classification scheme and reviews typical MR imaging findings of adult primary CNS neoplasms, including diffuse infiltrating gliomas, ependymal tumors, neuronal/glioneuronal tumors, pineal gland tumors, meningiomas, nerve sheath tumors, solitary fibrous tumors, and lymphoma.
KW - Adult primary neoplasm
KW - Central nervous system
KW - MR imaging
KW - WHO
UR - http://www.scopus.com/inward/record.url?scp=85070662351&partnerID=8YFLogxK
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U2 - 10.1016/j.rcl.2019.07.004
DO - 10.1016/j.rcl.2019.07.004
M3 - Review article
C2 - 31582041
AN - SCOPUS:85070662351
SN - 0033-8389
VL - 57
SP - 1147
EP - 1162
JO - Radiologic Clinics of North America
JF - Radiologic Clinics of North America
IS - 6
ER -