Alcohol, stem cells and cancer

Shoujun Gu; Bao Ngoc Nguyen; Shuyun Rao; Shulin Li; Kirti Shetty; Asif Rashid; Vivek Shukla; Chu Xia Deng; Lopa Mishra; Bibhuti Mishra

doi:10.18632/genesandcancer.156

Alcohol, stem cells and cancer

Shoujun Gu, Bao Ngoc Nguyen, Shuyun Rao, Shulin Li, Kirti Shetty, Asif Rashid, Vivek Shukla, Chu Xia Deng, Lopa Mishra, Bibhuti Mishra

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

Original language	English (US)
Pages (from-to)	695-700
Number of pages	6
Journal	Genes and Cancer
Volume	8
Issue number	9-10
DOIs	https://doi.org/10.18632/genesandcancer.156
State	Published - Sep 2017

Keywords

Alcohol
Cancer
DNA repair
Stem cells
TGF-β

ASJC Scopus subject areas

Genetics
Cancer Research

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10.18632/genesandcancer.156

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title = "Alcohol, stem cells and cancer",

abstract = "Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.",

keywords = "Alcohol, Cancer, DNA repair, Stem cells, TGF-β",

author = "Shoujun Gu and Nguyen, {Bao Ngoc} and Shuyun Rao and Shulin Li and Kirti Shetty and Asif Rashid and Vivek Shukla and Deng, {Chu Xia} and Lopa Mishra and Bibhuti Mishra",

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AU - Gu, Shoujun

AU - Nguyen, Bao Ngoc

AU - Rao, Shuyun

AU - Li, Shulin

AU - Shetty, Kirti

AU - Rashid, Asif

AU - Shukla, Vivek

AU - Deng, Chu Xia

AU - Mishra, Lopa

AU - Mishra, Bibhuti

N1 - Publisher Copyright: © Gu et al.

PY - 2017/9

Y1 - 2017/9

N2 - Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

AB - Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

KW - Alcohol

KW - Cancer

KW - DNA repair

KW - Stem cells

KW - TGF-β

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JF - Genes and Cancer

IS - 9-10

ER -

Alcohol, stem cells and cancer

Abstract

Keywords

ASJC Scopus subject areas

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