Abstract
Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 695-700 |
| Number of pages | 6 |
| Journal | Genes and Cancer |
| Volume | 8 |
| Issue number | 9-10 |
| DOIs | |
| State | Published - Sep 2017 |
Keywords
- Alcohol
- Cancer
- DNA repair
- Stem cells
- TGF-β
ASJC Scopus subject areas
- Genetics
- Cancer Research
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