Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells

A. E. van der Merwe; F. J. Mattheyse; M. Bedford; P. D. van Helden; D. J. Rossouw

doi:10.1016/0305-4179(90)90038-X

Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells

A. E. van der Merwe
, F. J. Mattheyse
, M. Bedford
, P. D. van Helden
, D. J. Rossouw

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Cultured keratinocytes were used as allografts on burn wounds in two patients. In both patients successful covering of the wounds was obtained. DNA fingerprinting of the epidermis covering the wounds 21 days later showed that the cultured keratinocytes were replaced by the patients' cells.

Original language	English (US)
Pages (from-to)	193-197
Number of pages	5
Journal	Burns
Volume	16
Issue number	3
DOIs	https://doi.org/10.1016/0305-4179(90)90038-X
State	Published - Jun 1990
Externally published	Yes

ASJC Scopus subject areas

Surgery
Emergency Medicine
Critical Care and Intensive Care Medicine

Access to Document

10.1016/0305-4179(90)90038-X

Cite this

@article{5866fb1ebd1149ca8cfb13c459e0314b,

title = "Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells",

abstract = "Cultured keratinocytes were used as allografts on burn wounds in two patients. In both patients successful covering of the wounds was obtained. DNA fingerprinting of the epidermis covering the wounds 21 days later showed that the cultured keratinocytes were replaced by the patients' cells.",

author = "\{van der Merwe\}, \{A. E.\} and Mattheyse, \{F. J.\} and M. Bedford and \{van Helden\}, \{P. D.\} and Rossouw, \{D. J.\}",

note = "Funding Information: We thank Mr M. Blom for technical assistance in culturing the keratinocytes, and ICI (UK) for permission to use the 33.6 Jeffreys human satellite DNA probe. The probes 33.6 and 33.15 are the subject of patent property and commercial enquiries regarding these probes should be directed to ICI Diagnostics, Gadbrook Park, R\&heath, Northwich, Cheshire, CW9 X4, UK. We express our gratitude to the Department of Radiotherapy, Tygerberg Hospital, for making a Vo source available for the irradiation of the 3T3 cells. We acknowledge financial assistance from the South African Medical Research Council.",

year = "1990",

month = jun,

doi = "10.1016/0305-4179(90)90038-X",

language = "English (US)",

volume = "16",

pages = "193--197",

journal = "Burns",

issn = "0305-4179",

publisher = "Elsevier Ltd",

number = "3",

}

TY - JOUR

T1 - Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells

AU - van der Merwe, A. E.

AU - Mattheyse, F. J.

AU - Bedford, M.

AU - van Helden, P. D.

AU - Rossouw, D. J.

N1 - Funding Information: We thank Mr M. Blom for technical assistance in culturing the keratinocytes, and ICI (UK) for permission to use the 33.6 Jeffreys human satellite DNA probe. The probes 33.6 and 33.15 are the subject of patent property and commercial enquiries regarding these probes should be directed to ICI Diagnostics, Gadbrook Park, R&heath, Northwich, Cheshire, CW9 X4, UK. We express our gratitude to the Department of Radiotherapy, Tygerberg Hospital, for making a Vo source available for the irradiation of the 3T3 cells. We acknowledge financial assistance from the South African Medical Research Council.

PY - 1990/6

Y1 - 1990/6

N2 - Cultured keratinocytes were used as allografts on burn wounds in two patients. In both patients successful covering of the wounds was obtained. DNA fingerprinting of the epidermis covering the wounds 21 days later showed that the cultured keratinocytes were replaced by the patients' cells.

AB - Cultured keratinocytes were used as allografts on burn wounds in two patients. In both patients successful covering of the wounds was obtained. DNA fingerprinting of the epidermis covering the wounds 21 days later showed that the cultured keratinocytes were replaced by the patients' cells.

UR - https://www.scopus.com/pages/publications/0025026093

UR - https://www.scopus.com/pages/publications/0025026093#tab=citedBy

U2 - 10.1016/0305-4179(90)90038-X

DO - 10.1016/0305-4179(90)90038-X

M3 - Article

C2 - 2383360

AN - SCOPUS:0025026093

SN - 0305-4179

VL - 16

SP - 193

EP - 197

JO - Burns

JF - Burns

IS - 3

ER -

Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this