An expanded cohort study of cancer among benzene-exposed workers in China

Song Nian Yin, Richard B. Hayes, Martha S. Linet, Gui Lan Li, Mustafa Dosemeci, Lois B. Travis, Zhi Nan Zhang, De Gao Li, Wong-Ho Chow, Sholom Wacholder, William J. Blot, Y. Z. Wang, Z. L. Jiang, T. R. Dai, W. Y. Zhang, X. Y. Chao, P. Z. Ye, Q. R. Kou, X. C. Chang, X. F. LinJ. F. Meng, C. Y. Ding, J. S. Zho

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Abstract

An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1.2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia.

Original languageEnglish (US)
Pages (from-to)1339-1341
Number of pages3
JournalEnvironmental Health Perspectives
Volume104
Issue numberSUPPL. 6
StatePublished - Dec 1 1996

Fingerprint

Benzene
benzene
cancer
China
Cohort Studies
Neoplasms
Leukemia
anemia
Aplastic Anemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
Lymphoma
Lung Neoplasms
leukaemia
mortality
Mortality

Keywords

  • Aplastic anemia
  • Benzene
  • Leukemia
  • Lung cancer
  • Malignant lymphoma

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Yin, S. N., Hayes, R. B., Linet, M. S., Li, G. L., Dosemeci, M., Travis, L. B., ... Zho, J. S. (1996). An expanded cohort study of cancer among benzene-exposed workers in China. Environmental Health Perspectives, 104(SUPPL. 6), 1339-1341.

An expanded cohort study of cancer among benzene-exposed workers in China. / Yin, Song Nian; Hayes, Richard B.; Linet, Martha S.; Li, Gui Lan; Dosemeci, Mustafa; Travis, Lois B.; Zhang, Zhi Nan; Li, De Gao; Chow, Wong-Ho; Wacholder, Sholom; Blot, William J.; Wang, Y. Z.; Jiang, Z. L.; Dai, T. R.; Zhang, W. Y.; Chao, X. Y.; Ye, P. Z.; Kou, Q. R.; Chang, X. C.; Lin, X. F.; Meng, J. F.; Ding, C. Y.; Zho, J. S.

In: Environmental Health Perspectives, Vol. 104, No. SUPPL. 6, 01.12.1996, p. 1339-1341.

Research output: Contribution to journalArticle

Yin, SN, Hayes, RB, Linet, MS, Li, GL, Dosemeci, M, Travis, LB, Zhang, ZN, Li, DG, Chow, W-H, Wacholder, S, Blot, WJ, Wang, YZ, Jiang, ZL, Dai, TR, Zhang, WY, Chao, XY, Ye, PZ, Kou, QR, Chang, XC, Lin, XF, Meng, JF, Ding, CY & Zho, JS 1996, 'An expanded cohort study of cancer among benzene-exposed workers in China', Environmental Health Perspectives, vol. 104, no. SUPPL. 6, pp. 1339-1341.
Yin SN, Hayes RB, Linet MS, Li GL, Dosemeci M, Travis LB et al. An expanded cohort study of cancer among benzene-exposed workers in China. Environmental Health Perspectives. 1996 Dec 1;104(SUPPL. 6):1339-1341.
Yin, Song Nian ; Hayes, Richard B. ; Linet, Martha S. ; Li, Gui Lan ; Dosemeci, Mustafa ; Travis, Lois B. ; Zhang, Zhi Nan ; Li, De Gao ; Chow, Wong-Ho ; Wacholder, Sholom ; Blot, William J. ; Wang, Y. Z. ; Jiang, Z. L. ; Dai, T. R. ; Zhang, W. Y. ; Chao, X. Y. ; Ye, P. Z. ; Kou, Q. R. ; Chang, X. C. ; Lin, X. F. ; Meng, J. F. ; Ding, C. Y. ; Zho, J. S. / An expanded cohort study of cancer among benzene-exposed workers in China. In: Environmental Health Perspectives. 1996 ; Vol. 104, No. SUPPL. 6. pp. 1339-1341.
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