An expanded cohort study of cancer among benzene-exposed workers in China

Song Nian Yin; Richard B. Hayes; Martha S. Linet; Gui Lan Li; Mustafa Dosemeci; Lois B. Travis; Zhi Nan Zhang; De Gao Li; Wong Ho Chow; Sholom Wacholder; William J. Blot; Y. Z. Wang; Z. L. Jiang; T. R. Dai; W. Y. Zhang; X. Y. Chao; P. Z. Ye; Q. R. Kou; X. C. Chang; X. F. Lin; J. F. Meng; C. Y. Ding; J. S. Zho

doi:10.1289/ehp.961041339

An expanded cohort study of cancer among benzene-exposed workers in China

Song Nian Yin, Richard B. Hayes, Martha S. Linet, Gui Lan Li, Mustafa Dosemeci, Lois B. Travis, Zhi Nan Zhang, De Gao Li, Wong Ho Chow, Sholom Wacholder, William J. Blot, Y. Z. Wang, Z. L. Jiang, T. R. Dai, W. Y. Zhang, X. Y. Chao, P. Z. Ye, Q. R. Kou, X. C. Chang, X. F. LinJ. F. Meng, C. Y. Ding, J. S. Zho

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108 Scopus citations

Abstract

An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1.2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia.

Original language	English (US)
Pages (from-to)	1339-1341
Number of pages	3
Journal	Environmental Health Perspectives
Volume	104
Issue number	SUPPL. 6
DOIs	https://doi.org/10.1289/ehp.961041339
State	Published - Dec 1996
Externally published	Yes

Keywords

Aplastic anemia
Benzene
Leukemia
Lung cancer
Malignant lymphoma

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

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10.1289/ehp.961041339

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Yin, S. N., Hayes, R. B., Linet, M. S., Li, G. L., Dosemeci, M., Travis, L. B., Zhang, Z. N., Li, D. G., Chow, W. H., Wacholder, S., Blot, W. J., Wang, Y. Z., Jiang, Z. L., Dai, T. R., Zhang, W. Y., Chao, X. Y., Ye, P. Z., Kou, Q. R., Chang, X. C., ... Zho, J. S. (1996). An expanded cohort study of cancer among benzene-exposed workers in China. Environmental Health Perspectives, 104(SUPPL. 6), 1339-1341. https://doi.org/10.1289/ehp.961041339

Yin, SN, Hayes, RB, Linet, MS, Li, GL, Dosemeci, M, Travis, LB, Zhang, ZN, Li, DG, Chow, WH, Wacholder, S, Blot, WJ, Wang, YZ, Jiang, ZL, Dai, TR, Zhang, WY, Chao, XY, Ye, PZ, Kou, QR, Chang, XC, Lin, XF, Meng, JF, Ding, CY & Zho, JS 1996, 'An expanded cohort study of cancer among benzene-exposed workers in China', Environmental Health Perspectives, vol. 104, no. SUPPL. 6, pp. 1339-1341. https://doi.org/10.1289/ehp.961041339

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abstract = "An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1.2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia.",

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AU - Blot, William J.

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AU - Zhang, W. Y.

AU - Chao, X. Y.

AU - Ye, P. Z.

AU - Kou, Q. R.

AU - Chang, X. C.

AU - Lin, X. F.

AU - Meng, J. F.

AU - Ding, C. Y.

AU - Zho, J. S.

PY - 1996/12

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An expanded cohort study of cancer among benzene-exposed workers in China

Abstract

Keywords

ASJC Scopus subject areas

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