TY - JOUR
T1 - An update on cancer-related fatigue in older adults
T2 - A narrative review
AU - Soones, Tacara
AU - Ombres, Rachel
AU - Escalante, Carmen
N1 - Funding Information:
The authors would like to thank The University of Texas MD Anderson Cancer Center's Research Medical Library, research librarian Yimin Geng for conducting the literature search, and scientific editor Laura L. Russell for providing editing services.
Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2022/3
Y1 - 2022/3
N2 - Up to 70% of older adults report fatigue after a cancer diagnosis. For many of these patients, cancer-related fatigue (CRF) persists for years after cancer treatment and is associated with significant disability. Despite this, little has been written on the diagnosis and management of CRF in older adults. To address this gap, we performed a narrative review of the literature on CRF in older adults and used literature from the general population when evidence was lacking to provide guidance to clinical providers on how to tailor care to this population. We recommend evidence-based options for evaluating CRF and address their limitations in the assessment of older adults. We also provide guidance and a treatment algorithm on evaluating CRF using the Comprehensive Geriatrics Assessment. Lastly, we present evidence for the use of non-pharmacologic and pharmacologic therapies in the management of CRF in older adults.
AB - Up to 70% of older adults report fatigue after a cancer diagnosis. For many of these patients, cancer-related fatigue (CRF) persists for years after cancer treatment and is associated with significant disability. Despite this, little has been written on the diagnosis and management of CRF in older adults. To address this gap, we performed a narrative review of the literature on CRF in older adults and used literature from the general population when evidence was lacking to provide guidance to clinical providers on how to tailor care to this population. We recommend evidence-based options for evaluating CRF and address their limitations in the assessment of older adults. We also provide guidance and a treatment algorithm on evaluating CRF using the Comprehensive Geriatrics Assessment. Lastly, we present evidence for the use of non-pharmacologic and pharmacologic therapies in the management of CRF in older adults.
KW - Cancer-related fatigue
KW - Non-pharmacologic interventions
KW - Pharmacologic interventions
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U2 - 10.1016/j.jgo.2021.07.006
DO - 10.1016/j.jgo.2021.07.006
M3 - Review article
C2 - 34353750
AN - SCOPUS:85111843360
SN - 1879-4068
VL - 13
SP - 125
EP - 131
JO - Journal of Geriatric Oncology
JF - Journal of Geriatric Oncology
IS - 2
ER -