Abstract
Benzodiazepines (BZDs) are commonly prescribed for pancreatic cancer patients. To investigate the correlation between BZDs and survival outcomes a recent study by Cornwell et al. found that lorazepam (LOR) correlates with poor survival. The mechanistic study shows that LOR increases interleukin 6 (IL6) expression in cancer-associated fibroblasts via GPR68.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 874-875 |
| Number of pages | 2 |
| Journal | Trends in Cancer |
| Volume | 9 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2023 |
Keywords
- benzodiazepines
- fibroblast
- GPR68
- interleukin 6
- pancreatic cancer
- survival
ASJC Scopus subject areas
- Oncology
- Cancer Research
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