Appendicitis Post Immune Checkpoint Inhibitor Therapy

Antony Mathew; Yang Lu; Malek Shatila; Yinghong Wang; Nizar M. Tannir; Bilal Siddiqui

doi:10.1007/978-3-031-83533-9_12

Appendicitis Post Immune Checkpoint Inhibitor Therapy

Antony Mathew
, Yang Lu
, Malek Shatila
, Yinghong Wang
, Nizar M. Tannir
, Bilal Siddiqui

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

We presented a male patient in his 50s with metastatic prostate cancer on treatment with ipilimumab who presented with 10 days of abdominal pain and was found to have perforated appendicitis with abscess. Given clinical stability, reassuring physical exam and laboratory workup, the patient was managed conservatively with antibiotics and without surgery or abscess drainage. Interval CT imaging on antibiotic treatment showed improvement in intrabdominal findings.

Original language	English (US)
Title of host publication	Challenging Cases in Immunotherapy Related Organ Toxicities
Publisher	Springer Science+Business Media
Pages	89-94
Number of pages	6
ISBN (Electronic)	9783031835339
ISBN (Print)	9783031835322
DOIs	https://doi.org/10.1007/978-3-031-83533-9_12
State	Published - Jan 1 2025

Keywords

Adverse event
Appendicitis
Immune checkpoint inhibitors
Toxicity

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-031-83533-9_12

Cite this

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AU - Mathew, Antony

AU - Lu, Yang

AU - Shatila, Malek

AU - Wang, Yinghong

AU - Tannir, Nizar M.

AU - Siddiqui, Bilal

PY - 2025/1/1

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AB - We presented a male patient in his 50s with metastatic prostate cancer on treatment with ipilimumab who presented with 10 days of abdominal pain and was found to have perforated appendicitis with abscess. Given clinical stability, reassuring physical exam and laboratory workup, the patient was managed conservatively with antibiotics and without surgery or abscess drainage. Interval CT imaging on antibiotic treatment showed improvement in intrabdominal findings.

KW - Adverse event

KW - Appendicitis

KW - Immune checkpoint inhibitors

KW - Toxicity

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ER -

Appendicitis Post Immune Checkpoint Inhibitor Therapy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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