Abstract
Application of RET proto-oncogene mutation analysis to the clinical management of MEN 2 and FMTC has simplified and enhanced the power of earlier used screening and treatment efforts for hereditary MTC. The approaches outlined herein are cost-effective, have improved diagnostic accuracy, and hold the promise of improved cure rates for this neoplasm. Further studies to elucidate the mechanism by which these activating mutations cause transformation may lead to other strategies for prevention or treatment of this neoplasm.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-25 |
| Number of pages | 25 |
| Journal | Endocrinology and Metabolism Clinics of North America |
| Volume | 25 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1996 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology
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