Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

Irving Weinberg; David Beylin; Steve Yarnall; Edward Anashkin; Pavel Stepanov; Sevgei Dolinsky; Valera Zavarzin; William Peter; Kathrin Lauckner; Kathryn Morton; Rita Freimanis; Nadia Lesko; Edward Levine; Nancy Perrier; Judy Lovelace; Kim Geisinger; Rodney Williams; Scott Wollenweber; Deepa Narayanan; Mohan Doss; Jean Hummel; Elin Sigurdson; Kathryn Evers; Michael Torosian; Lee Adler

Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

Irving Weinberg, David Beylin, Steve Yarnall, Edward Anashkin, Pavel Stepanov, Sevgei Dolinsky, Valera Zavarzin, William Peter, Kathrin Lauckner, Kathryn Morton, Rita Freimanis, Nadia Lesko, Edward Levine, Nancy Perrier, Judy Lovelace, Kim Geisinger, Rodney Williams, Scott Wollenweber, Deepa Narayanan, Mohan DossJean Hummel, Elin Sigurdson, Kathryn Evers, Michael Torosian, Lee Adler

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

11 Scopus citations

Abstract

Operation of a high resolution compact clinical PET Scanner (PEM Flex™) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.

Original language	English (US)
Title of host publication	2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	Macro to Nano
Pages	1396-1399
Number of pages	4
State	Published - 2004
Externally published	Yes
Event	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States Duration: Apr 15 2004 → Apr 18 2004

Publication series

Name	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume	2

Other

Other	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/Territory	United States
City	Arlington, VA
Period	4/15/04 → 4/18/04

ASJC Scopus subject areas

General Engineering

Cite this

Weinberg, I., Beylin, D., Yarnall, S., Anashkin, E., Stepanov, P., Dolinsky, S., Zavarzin, V., Peter, W., Lauckner, K., Morton, K., Freimanis, R., Lesko, N., Levine, E., Perrier, N., Lovelace, J., Geisinger, K., Williams, R., Wollenweber, S., Narayanan, D., ... Adler, L. (2004). Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 1396-1399). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).

Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging. / Weinberg, Irving; Beylin, David; Yarnall, Steve et al.
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004. p. 1396-1399 (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Weinberg, I, Beylin, D, Yarnall, S, Anashkin, E, Stepanov, P, Dolinsky, S, Zavarzin, V, Peter, W, Lauckner, K, Morton, K, Freimanis, R, Lesko, N, Levine, E, Perrier, N, Lovelace, J, Geisinger, K, Williams, R, Wollenweber, S, Narayanan, D, Doss, M, Hummel, J, Sigurdson, E, Evers, K, Torosian, M & Adler, L 2004, Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging. in 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 2, pp. 1396-1399, 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, Arlington, VA, United States, 4/15/04.

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abstract = "Operation of a high resolution compact clinical PET Scanner (PEM Flex{\texttrademark}) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.",

author = "Irving Weinberg and David Beylin and Steve Yarnall and Edward Anashkin and Pavel Stepanov and Sevgei Dolinsky and Valera Zavarzin and William Peter and Kathrin Lauckner and Kathryn Morton and Rita Freimanis and Nadia Lesko and Edward Levine and Nancy Perrier and Judy Lovelace and Kim Geisinger and Rodney Williams and Scott Wollenweber and Deepa Narayanan and Mohan Doss and Jean Hummel and Elin Sigurdson and Kathryn Evers and Michael Torosian and Lee Adler",

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AU - Dolinsky, Sevgei

AU - Zavarzin, Valera

AU - Peter, William

AU - Lauckner, Kathrin

AU - Morton, Kathryn

AU - Freimanis, Rita

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AU - Geisinger, Kim

AU - Williams, Rodney

AU - Wollenweber, Scott

AU - Narayanan, Deepa

AU - Doss, Mohan

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AU - Sigurdson, Elin

AU - Evers, Kathryn

AU - Torosian, Michael

AU - Adler, Lee

PY - 2004

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AB - Operation of a high resolution compact clinical PET Scanner (PEM Flex™) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic x-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within x-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with three-fold improved contrast as compared to simple back-projections.

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M3 - Conference contribution

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T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

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BT - 2004 2nd IEEE International Symposium on Biomedical Imaging

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ER -

Applications of a pet device with 1.5 MM FWHM intrinsic spatial resolution to breast cancer imaging

Abstract

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ASJC Scopus subject areas

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