TY - JOUR
T1 - Area Deprivation Index is Associated with Variation in Quality of Life and Psychosocial Well-being Following Breast Cancer Surgery
AU - Hassan, Abbas M.
AU - Nguyen, Huan T.
AU - Corkum, Joseph P.
AU - Liu, Jun
AU - Kapur, Sahil K.
AU - Chu, Carrie K.
AU - Tamirisa, Nina
AU - Offodile, Anaeze C.
N1 - Funding Information:
Dr. Offodile reports research funding from Blue Cross Blue Shield Affordability Cures Research Consortium, University Cancer Foundation, Rising Tide Foundation for Clinical Cancer Research, and the National Academy of Medicine. Dr. Offodile also is an unpaid board member of the Patient Advocate Foundation and reports honorarium from the Indiana University and University of Tennessee. All are unrelated to the submitted work. The other authors have no financial or non-financial disclosures.
Publisher Copyright:
© 2022, Society of Surgical Oncology.
PY - 2023/1
Y1 - 2023/1
N2 - Background: Neighborhood-level factors have been shown to influence surgical outcomes through material deprivation, psychosocial mechanisms, health behaviors, and access to resources. To date, no study has examined the relationship between area-level deprivation (ADI) and post-mastectomy outcomes. Methods: A cross-sectional survey of adult female breast cancer patients who underwent lumpectomy or mastectomy between January 2018 to June 2019 was carried out. Patient-specific characteristics and ADI information were abstracted and correlated with postoperative global- (SF-12) and condition-specific (BREAST-Q) quality-of-life performance via multivariable regression. Patients were classified into three ADI terciles: 0–39 (low deprivation), 40–59 (moderate deprivation), and 60–100 (high deprivation). Results: A total of 564 consecutive patients were identified, being mostly white (75%) with mean age of 60.2 ± 12.4 years, median body mass index of 27.8 [interquartile range (IQR) 24.3–32.2) kg/m2, median Charlson Comorbidity Index of 3 (IQR 2–5), and mean ADI of 42.3 ± 25.7. African American and Hispanic patients and those with high BMI were more likely to reside in highly deprived neighborhoods (p = 0.003 and p < 0.001). In adjusted models, patients in highly deprived neighborhoods had significantly lower mean SF-12 physical (44.9 [95% CI, 43.8–46.0] versus 44.9 [95% CI, 43.7–46.1] versus 46.3 [95% CI, 45.3–47.3], p = 0.03) and BREAST-Q psychosocial well-being scores (63.5 [95% CI, 59.32–67.8] versus 69.3 [95% CI, 65.1–73.6] versus 69.7 [95% CI, 66.4-73.1], p = 0.01) relative to moderate- and low-deprivation groups. Conclusions: Patients residing in the most deprived neighborhoods were identified to have worse psychological well-being and quality-of-life. The ADI should be incorporated into the shared decision-making process and perioperative counseling to engender value-based and personalized care, especially for vulnerable populations.
AB - Background: Neighborhood-level factors have been shown to influence surgical outcomes through material deprivation, psychosocial mechanisms, health behaviors, and access to resources. To date, no study has examined the relationship between area-level deprivation (ADI) and post-mastectomy outcomes. Methods: A cross-sectional survey of adult female breast cancer patients who underwent lumpectomy or mastectomy between January 2018 to June 2019 was carried out. Patient-specific characteristics and ADI information were abstracted and correlated with postoperative global- (SF-12) and condition-specific (BREAST-Q) quality-of-life performance via multivariable regression. Patients were classified into three ADI terciles: 0–39 (low deprivation), 40–59 (moderate deprivation), and 60–100 (high deprivation). Results: A total of 564 consecutive patients were identified, being mostly white (75%) with mean age of 60.2 ± 12.4 years, median body mass index of 27.8 [interquartile range (IQR) 24.3–32.2) kg/m2, median Charlson Comorbidity Index of 3 (IQR 2–5), and mean ADI of 42.3 ± 25.7. African American and Hispanic patients and those with high BMI were more likely to reside in highly deprived neighborhoods (p = 0.003 and p < 0.001). In adjusted models, patients in highly deprived neighborhoods had significantly lower mean SF-12 physical (44.9 [95% CI, 43.8–46.0] versus 44.9 [95% CI, 43.7–46.1] versus 46.3 [95% CI, 45.3–47.3], p = 0.03) and BREAST-Q psychosocial well-being scores (63.5 [95% CI, 59.32–67.8] versus 69.3 [95% CI, 65.1–73.6] versus 69.7 [95% CI, 66.4-73.1], p = 0.01) relative to moderate- and low-deprivation groups. Conclusions: Patients residing in the most deprived neighborhoods were identified to have worse psychological well-being and quality-of-life. The ADI should be incorporated into the shared decision-making process and perioperative counseling to engender value-based and personalized care, especially for vulnerable populations.
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U2 - 10.1245/s10434-022-12506-z
DO - 10.1245/s10434-022-12506-z
M3 - Article
C2 - 36085393
AN - SCOPUS:85137767914
SN - 1068-9265
VL - 30
SP - 80
EP - 87
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
IS - 1
ER -