Aromatic DNA adducts in white blood cells of coke workers

K. Hemminki, E. Grzybowska, M. Chorazy, K. Twardowska-Saucha, J. W. Sroczynski, K. L. Putman, K. Randerath, D. H. Phillips, A. Hewer

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    41 Scopus citations


    White blood cell DNA adducts were measured in coke workers, local controls and countryside controls using the 32P-postlabelling technique. The method detected aromatic adducts including those formed by polycyclic aromatic hydrocarbons (PAHs). Coke workers are heavily exposed to PAHs particularly when working at the batteries. A difference in adduct levels was noted between the coke workers at the battery as compared to other jobs. The adduct levels in the non-battery were higher than those in the countryside controls.

    Original languageEnglish (US)
    Pages (from-to)467-470
    Number of pages4
    JournalInternational Archives of Occupational and Environmental Health
    Issue number6
    StatePublished - Oct 1 1990


    • DNA adducts
    • P-postlabelling
    • PAH
    • White blood cell

    ASJC Scopus subject areas

    • Public Health, Environmental and Occupational Health

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    Hemminki, K., Grzybowska, E., Chorazy, M., Twardowska-Saucha, K., Sroczynski, J. W., Putman, K. L., Randerath, K., Phillips, D. H., & Hewer, A. (1990). Aromatic DNA adducts in white blood cells of coke workers. International Archives of Occupational and Environmental Health, 62(6), 467-470.