Abstract
Background: This study reports long-term head and neck cancer (HNC) patient-reported symptoms using the MD Anderson Symptom Inventory Head and Neck Cancer Module (MDASI-HN) in a large cohort of HNC survivors. Methods: MDASI-HN results were prospectively collected from an institutional survivorship database. Associations with clinicopathologic data were analyzed using χ2, Mann-Whitney, and univariate regression. Results: Nine hundred and twenty-eight patients were included. Forty-six percent had oropharyngeal primary tumors. Eighty-two percent had squamous cell carcinoma. Fifty-six percent of patients had ablative surgery and 81% had radiation therapy as a component of treatment. The most severe symptoms were xerostomia and dysphagia. Symptom scores were worst for hypopharynx and varied by subsite. Patients treated with chemoradiation or surgery followed by radiation ± chemotherapy reported the worst symptoms while patient treated with surgery plus radiation ± chemotherapy reported the worst interference. Conclusion: HNC survivors describe their long-term symptom burden and inform efforts to improve care many years into survivorship.
Original language | English (US) |
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Pages (from-to) | 1919-1927 |
Number of pages | 9 |
Journal | Head and Neck |
Volume | 42 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1 2020 |
ASJC Scopus subject areas
- Otorhinolaryngology