Assessment of demand for methamphetamine and cigarettes among individuals with methamphetamine use disorder.

Jin H. Yoon, Robert Suchting, Rachel N. Cassidy, Peter K. Bolin, Yasmine Omar, Gregory S. Brown, Richard De La Garza

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Methamphetamine (MA) is a highly addictive stimulant with recent upward trends in prevalence and associated public health problems. Drug demand, as assessed by hypothetical purchasing tasks, has been useful in addictions research and may help our understanding of the factors influencing MA use. However, no studies have assessed MA demand using current models of demand. The purpose of the current study was to assess demand for MA using a hypothetical drug purchasing task. Given high rates of cigarette smoking among MA users, it was of interest also to assess and compare demand for MA relative to cigarettes. Participants consisted of non-treatment-seeking volunteers with MA use disorder (N = 18), of whom 17 reported daily smoking. Results showed the exponentiated demand model provided a good fit to consumption data. Results from Bayesian generalized linear modeling demonstrated multiple positive relationships (posterior probability ≥75%) between self-reported drug use (days MA used in the past 30 days, cigarettes smoked per day) and indices of demand for each drug (Qo, Omax, Pmax, and break point). Comparing MA to cigarettes, results from Bayesian generalized linear mixed modeling revealed greater abuse liability for MA compared to cigarettes (posterior probability ≥99%) based on α and essential value. Overall, the findings of the current study support the feasibility and validity of the exponentiated demand model for assessing demand for drugs among individuals with MA use disorder. (PsycInfo Database Record (c) 2021 APA, all rights reserved) Public Health Significance—Methamphetamine is a significant public health concern with increasing negative impact. Behavioral economic measures, such as drug demand, may provide key insight into the decision making processes involved in methamphetamine use.

Original languageEnglish (US)
Pages (from-to)334-344
Number of pages11
JournalExperimental and clinical psychopharmacology
Volume29
Issue number4
DOIs
StatePublished - Aug 2021
Externally publishedYes

Keywords

  • behavioral economics
  • cigarettes
  • demand
  • methamphetamine
  • nicotine

ASJC Scopus subject areas

  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)

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