Basal cell carcinoma with matrical differentiation: A case study with analysis of β-catenin

Henry D. Haskell, Harley A. Haynes, Phillip H. McKee, Mark Redston, Scott R. Granter, Alexander J.F. Lazar

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Matrical differentiation in basal cell carcinoma (BCC) is rare. Only nine cases have been described that showed typical diagnostic features of BCC. in addition to shadow cells indicating hair-matrix differentiation. These cases often present a diagnostic challenge due to confusion with pilomatrixoma or pilomatrix carcinoma. We present a case of BCC with matrical differentiation in a 78-year-old man. Immunohistochemical and molecular methods are used to differentiate this lesion from benign or malignant forms of pilomatrixoma.

Original languageEnglish (US)
Pages (from-to)245-250
Number of pages6
JournalJournal of cutaneous pathology
Volume32
Issue number3
DOIs
StatePublished - Mar 2005

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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