Binding of HIV gp41 with its receptors immobilized at liquid/solid interface studied by surface plasmon resonance

Jun Yang, Yutong Sun, Weichen Wu, Yinghua Chen, Sen Fang Sui

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A home-made SPR biosensor was used to monitor the interactions of gp41 with its binding proteins in real time. The result indicates that the polystyrene biosensor film is useful for SPR detection. The binding constants indicate both P45 and P62 have a high affinity to the protein gp41, and suggest that P45 and P62 may be the cellular receptors on human T-, B-lymphocytes and monocytcs.

Original languageEnglish (US)
Pages (from-to)465-468
Number of pages4
JournalMolecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals
Volume337
DOIs
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Condensed Matter Physics

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