TY - JOUR
T1 - Biologic effects of dopamine on tumor vasculature in ovarian carcinoma
AU - Moreno-Smith, Myrthala
AU - Lee, Sun Joo
AU - Chunhua, Lu
AU - Nagaraja, Archana S.
AU - He, Guangan
AU - Rupaimoole, Rajesha
AU - Han, Hee Dong
AU - Jennings, Nicholas B.
AU - Roh, Ju Won
AU - Nishimura, Masato
AU - Kang, Yu
AU - Allen, Julie K.
AU - Armaiz, Guillermo N.
AU - Matsuo, Koji
AU - Shahzad, Mian M.K.
AU - Bottsford-Miller, Justin
AU - Langley, Robert R.
AU - Cole, Steve W.
AU - Lutgendorf, Susan K.
AU - Siddik, Zahid H.
AU - Sood, Anil K.
N1 - Funding Information:
Address all correspondence to: Anil K. Sood, MD, Professor, The University of Texas MD Anderson Cancer Center, 1155 Hermann Pressler Drive, Unit 1362,Houston, TX 77030. E-mail: [email protected] 1G.N.A. was supported in part by National Cancer Institute F31CA126474 Fellowship for Minority Students. J.B.-M. was supported by National Institute of Health (NIH) T32 Training grant CA101642. M.M.K.S. was supported by the GCF-Molly Cade ovarian cancer research grant and the NIH/Eunice Kennedy Shriver National Institute of Child Health Baylor Woman’s Reproductive Health Research scholarship grant. This work was also supported in part by NIH grants (CA109298, P50CA083639, P50CA098258, CA128797, RC2GM092599, U54CA151668, U54CA96300, U54CA96297, and CA160687), Ovarian Cancer Research Fund Program Project Development grant, Department of Defense (OC073399, W81XWH-10-1-0158, OC100237, and BC085265), the Cancer Prevention Research Institute of Texas (CPRIT) grant (RP110595), the Zarrow Foundation7, the Betty Ann Asche Murray Distinguished Professorship, the Marcus Foundation, the RGK Foundation, the Gilder Foundation, the estate of C.G. Johnson Jr, the Laura and John Arnold Foundation, and the Blanton-Davis Ovarian Cancer Research Program. The authors disclose no potential conflicts of interest. 2This article refers to supplementary materials, which are designated by Figures W1 to W5 and are available online at www.neoplasia.com. 3These authors contributed equally to this work. Received 29 August 2012; Revised 27 February 2013; Accepted 4 March 2013 Copyright © 2013 Neoplasia Press, Inc. All rights reserved 1522-8002/13/$25.00 DOI 10.1593/neo.121412
PY - 2013/5
Y1 - 2013/5
N2 - Chronic sympathetic nervous system activation results in increased angiogenesis and tumor growth in orthotopic mouse models of ovarian carcinoma. However, the mechanistic effects of such activation on the tumor vasculature are not well understood. Dopamine (DA), an inhibitory catecholamine, regulates the functions of normal and abnormal blood vessels. Here, we examined whether DA, an inhibitory catecholamine, could block the effects of.
AB - Chronic sympathetic nervous system activation results in increased angiogenesis and tumor growth in orthotopic mouse models of ovarian carcinoma. However, the mechanistic effects of such activation on the tumor vasculature are not well understood. Dopamine (DA), an inhibitory catecholamine, regulates the functions of normal and abnormal blood vessels. Here, we examined whether DA, an inhibitory catecholamine, could block the effects of.
UR - https://www.scopus.com/pages/publications/84877049285
UR - https://www.scopus.com/pages/publications/84877049285#tab=citedBy
U2 - 10.1593/neo.121412
DO - 10.1593/neo.121412
M3 - Article
C2 - 23633922
AN - SCOPUS:84877049285
SN - 1522-8002
VL - 15
SP - 502
EP - 510
JO - Neoplasia (United States)
JF - Neoplasia (United States)
IS - 5
ER -