Abstract
Bone metastases are common and can profoundly influence the quality of life of cancer patients. Early and accurate detection is important for therapeutic planning, and imaging modalities such as computed tomography (CT), skeletal scintigraphy (bone scan), magnetic resonance imaging (MRI), and positron emission tomography with integrated CT or MRI (PET/CT and PET/MRI) can be used for this purpose. The therapeutic response criteria developed at the MD Anderson Cancer Center are specific for interpreting the behavior of bone metastases. Therapeutic interventions such as systemic therapy with bisphosphonates or radiopharmaceuticals, radiation therapy, surgery, and percutaneous techniques such as vertebroplasty or radiofrequency ablation are prolonging the lives of cancer patients, with a concomitant increase in skeletal metastasis–related complications. This chapter discusses the role of imaging in the detection and therapeutic response of bone metastases, with a discussion of systemic and focal treatment options.
Original language | English (US) |
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Title of host publication | Oncologic Imaging |
Subtitle of host publication | A Multidisciplinary Approach |
Publisher | Elsevier |
Pages | 587-605 |
Number of pages | 19 |
ISBN (Electronic) | 9780323695381 |
ISBN (Print) | 9780323796385 |
DOIs | |
State | Published - Jan 1 2022 |
Externally published | Yes |
Keywords
- Bisphosphonates
- Bone
- Imaging
- MD Anderson Criteria
- MDA Criteria
- Metastases
- Therapy
- Vertebroplasty
ASJC Scopus subject areas
- General Medicine