Bone Metastases

Colleen M. Costelloe, Patrick P. Lin, Hubert H. Chuang, Behrang Amini, Naoto T. Ueno, Sudpreeda Chainitikun, T. Kuan Yu, John E. Madewell

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Bone metastases are common and can profoundly influence the quality of life of cancer patients. Early and accurate detection is important for therapeutic planning, and imaging modalities such as computed tomography (CT), skeletal scintigraphy (bone scan), magnetic resonance imaging (MRI), and positron emission tomography with integrated CT or MRI (PET/CT and PET/MRI) can be used for this purpose. The therapeutic response criteria developed at the MD Anderson Cancer Center are specific for interpreting the behavior of bone metastases. Therapeutic interventions such as systemic therapy with bisphosphonates or radiopharmaceuticals, radiation therapy, surgery, and percutaneous techniques such as vertebroplasty or radiofrequency ablation are prolonging the lives of cancer patients, with a concomitant increase in skeletal metastasis–related complications. This chapter discusses the role of imaging in the detection and therapeutic response of bone metastases, with a discussion of systemic and focal treatment options.

Original languageEnglish (US)
Title of host publicationOncologic Imaging
Subtitle of host publicationA Multidisciplinary Approach
PublisherElsevier
Pages587-605
Number of pages19
ISBN (Electronic)9780323695381
ISBN (Print)9780323796385
DOIs
StatePublished - Jan 1 2022
Externally publishedYes

Keywords

  • Bisphosphonates
  • Bone
  • Imaging
  • MD Anderson Criteria
  • MDA Criteria
  • Metastases
  • Therapy
  • Vertebroplasty

ASJC Scopus subject areas

  • General Medicine

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