TY - JOUR
T1 - Bone Metastases
T2 - Mechanisms of the Metastatic Process, Imaging and Therapy
AU - Costelloe, Colleen M.
AU - Lin, Patrick P.
AU - Chuang, Hubert H.
AU - Amini, Behrang
AU - Chainitikun, Sudpreeda
AU - Yu, Tse Kuan
AU - Ueno, Naoto T.
AU - Murphy, William A.
AU - Madewell, John E.
N1 - Publisher Copyright:
© 2020
PY - 2021/4
Y1 - 2021/4
N2 - The mechanisms by which tumors metastasize to bone are complex. Upon the successful establishment of metastatic deposits in the skeleton, detection of the disease becomes essential for therapeutic planning. The roles of CT, skeletal scintigraphy, SPECT/CT, MRI, PET/CT and PET/MRI will be reviewed. Therapeutic response criteria specifically designed to evaluate bone metastases (MD Anderson/MDA criteria) can guide image interpretation. Knowledge of therapeutic strategies such as systemic therapy with bisphosphonates or radiopharmaceuticals, radiation therapy, surgery, and percutaneous interventions such as vertebroplasty and radiofrequency ablation can help the radiologist produce reports that will provide maximum benefit to clinicians and patients.
AB - The mechanisms by which tumors metastasize to bone are complex. Upon the successful establishment of metastatic deposits in the skeleton, detection of the disease becomes essential for therapeutic planning. The roles of CT, skeletal scintigraphy, SPECT/CT, MRI, PET/CT and PET/MRI will be reviewed. Therapeutic response criteria specifically designed to evaluate bone metastases (MD Anderson/MDA criteria) can guide image interpretation. Knowledge of therapeutic strategies such as systemic therapy with bisphosphonates or radiopharmaceuticals, radiation therapy, surgery, and percutaneous interventions such as vertebroplasty and radiofrequency ablation can help the radiologist produce reports that will provide maximum benefit to clinicians and patients.
UR - http://www.scopus.com/inward/record.url?scp=85090487185&partnerID=8YFLogxK
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U2 - 10.1053/j.sult.2020.08.016
DO - 10.1053/j.sult.2020.08.016
M3 - Article
C2 - 33814103
AN - SCOPUS:85090487185
SN - 0887-2171
VL - 42
SP - 164
EP - 183
JO - Seminars in Ultrasound, CT and MRI
JF - Seminars in Ultrasound, CT and MRI
IS - 2
ER -