Botulinum Toxin Injection for Lower Face and Oral Cavity Raynaud Phenomenon after Mandibulectomy, Free Fibula Reconstruction, and Radiation Therapy

Stefanos Boukovalas, Ashley C. Mays, Jesse Creed Selber

Research output: Contribution to journalArticle

Abstract

Isolated lingual and lower face Raynaud phenomenon without primary Raynaud of the digits is a very rare condition associated with chemoradiation therapy (RT) in previous reports. The condition, which more commonly presents in patients with a history of Raynaud disease, is often self-limiting, but vasodilating agents and steroids have been suggested as possible treatment options. Spasmodic torticollis is a different, more common entity, also associated with history of RT or previous head and neck surgery. We present a rare case of a patient who developed Raynaud phenomenon of the lower face and tongue in the presence of spasmodic torticollis after mandibulectomy and free fibula reconstruction followed by RT to the oral cavity and neck. Possible causes, pathophysiologic mechanisms and treatment options are discussed. This is the first report of botulinum toxin treatment of isolated secondary Raynaud phenomenon of the lower face and tongue.

LanguageEnglish (US)
Pages53-54
Number of pages2
JournalAnnals of plastic surgery
Volume82
Issue number1
DOIs
StatePublished - Jan 1 2019

Fingerprint

Raynaud Disease
Fibula
Botulinum Toxins
Mouth
Radiotherapy
Tongue
Torticollis
Injections
Neck
Therapeutics
Steroids
Head

Keywords

  • botulinum toxin
  • head and neck radiation
  • Raynaud phenomenon
  • spasmodic torticollis

ASJC Scopus subject areas

  • Surgery

Cite this

Botulinum Toxin Injection for Lower Face and Oral Cavity Raynaud Phenomenon after Mandibulectomy, Free Fibula Reconstruction, and Radiation Therapy. / Boukovalas, Stefanos; Mays, Ashley C.; Selber, Jesse Creed.

In: Annals of plastic surgery, Vol. 82, No. 1, 01.01.2019, p. 53-54.

Research output: Contribution to journalArticle

@article{7442bdb9620a4f0dac01a66a36a810b7,
title = "Botulinum Toxin Injection for Lower Face and Oral Cavity Raynaud Phenomenon after Mandibulectomy, Free Fibula Reconstruction, and Radiation Therapy",
abstract = "Isolated lingual and lower face Raynaud phenomenon without primary Raynaud of the digits is a very rare condition associated with chemoradiation therapy (RT) in previous reports. The condition, which more commonly presents in patients with a history of Raynaud disease, is often self-limiting, but vasodilating agents and steroids have been suggested as possible treatment options. Spasmodic torticollis is a different, more common entity, also associated with history of RT or previous head and neck surgery. We present a rare case of a patient who developed Raynaud phenomenon of the lower face and tongue in the presence of spasmodic torticollis after mandibulectomy and free fibula reconstruction followed by RT to the oral cavity and neck. Possible causes, pathophysiologic mechanisms and treatment options are discussed. This is the first report of botulinum toxin treatment of isolated secondary Raynaud phenomenon of the lower face and tongue.",
keywords = "botulinum toxin, head and neck radiation, Raynaud phenomenon, spasmodic torticollis",
author = "Stefanos Boukovalas and Mays, {Ashley C.} and Selber, {Jesse Creed}",
year = "2019",
month = "1",
day = "1",
doi = "10.1097/SAP.0000000000001622",
language = "English (US)",
volume = "82",
pages = "53--54",
journal = "Annals of Plastic Surgery",
issn = "0148-7043",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Botulinum Toxin Injection for Lower Face and Oral Cavity Raynaud Phenomenon after Mandibulectomy, Free Fibula Reconstruction, and Radiation Therapy

AU - Boukovalas, Stefanos

AU - Mays, Ashley C.

AU - Selber, Jesse Creed

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Isolated lingual and lower face Raynaud phenomenon without primary Raynaud of the digits is a very rare condition associated with chemoradiation therapy (RT) in previous reports. The condition, which more commonly presents in patients with a history of Raynaud disease, is often self-limiting, but vasodilating agents and steroids have been suggested as possible treatment options. Spasmodic torticollis is a different, more common entity, also associated with history of RT or previous head and neck surgery. We present a rare case of a patient who developed Raynaud phenomenon of the lower face and tongue in the presence of spasmodic torticollis after mandibulectomy and free fibula reconstruction followed by RT to the oral cavity and neck. Possible causes, pathophysiologic mechanisms and treatment options are discussed. This is the first report of botulinum toxin treatment of isolated secondary Raynaud phenomenon of the lower face and tongue.

AB - Isolated lingual and lower face Raynaud phenomenon without primary Raynaud of the digits is a very rare condition associated with chemoradiation therapy (RT) in previous reports. The condition, which more commonly presents in patients with a history of Raynaud disease, is often self-limiting, but vasodilating agents and steroids have been suggested as possible treatment options. Spasmodic torticollis is a different, more common entity, also associated with history of RT or previous head and neck surgery. We present a rare case of a patient who developed Raynaud phenomenon of the lower face and tongue in the presence of spasmodic torticollis after mandibulectomy and free fibula reconstruction followed by RT to the oral cavity and neck. Possible causes, pathophysiologic mechanisms and treatment options are discussed. This is the first report of botulinum toxin treatment of isolated secondary Raynaud phenomenon of the lower face and tongue.

KW - botulinum toxin

KW - head and neck radiation

KW - Raynaud phenomenon

KW - spasmodic torticollis

UR - http://www.scopus.com/inward/record.url?scp=85058492525&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85058492525&partnerID=8YFLogxK

U2 - 10.1097/SAP.0000000000001622

DO - 10.1097/SAP.0000000000001622

M3 - Article

VL - 82

SP - 53

EP - 54

JO - Annals of Plastic Surgery

T2 - Annals of Plastic Surgery

JF - Annals of Plastic Surgery

SN - 0148-7043

IS - 1

ER -