BRCA1 forks over new roles in DNA-damage response- before and beyond the breaks

Lei Li

doi:10.1016/j.molcel.2011.10.003

BRCA1 forks over new roles in DNA-damage response- before and beyond the breaks

Lei Li

Experimental Radiation Oncology

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

In this issue, Pathania et al. (2011) report the involvement of BRCA1 in ultraviolet (UV)-damage response at stalled replication forks, which extends the function of BRCA1 beyond its established role in the repair of DNA- double-strand breaks (DSBs), raising the complexity of how this tumor suppressor maintains genomic stability.

Original language	English (US)
Pages (from-to)	174-176
Number of pages	3
Journal	Molecular cell
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/j.molcel.2011.10.003
State	Published - Oct 21 2011

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2011.10.003

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title = "BRCA1 forks over new roles in DNA-damage response- before and beyond the breaks",

abstract = "In this issue, Pathania et al. (2011) report the involvement of BRCA1 in ultraviolet (UV)-damage response at stalled replication forks, which extends the function of BRCA1 beyond its established role in the repair of DNA- double-strand breaks (DSBs), raising the complexity of how this tumor suppressor maintains genomic stability.",

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AB - In this issue, Pathania et al. (2011) report the involvement of BRCA1 in ultraviolet (UV)-damage response at stalled replication forks, which extends the function of BRCA1 beyond its established role in the repair of DNA- double-strand breaks (DSBs), raising the complexity of how this tumor suppressor maintains genomic stability.

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BRCA1 forks over new roles in DNA-damage response- before and beyond the breaks

Abstract

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