Breast cancer in adolescents and young adults

Rebecca H. Johnson; Carey K. Anders; Jennifer K. Litton; Kathryn J. Ruddy; Archie Bleyer

doi:10.1002/pbc.27397

Breast cancer in adolescents and young adults

Rebecca H. Johnson, Carey K. Anders, Jennifer K. Litton, Kathryn J. Ruddy, Archie Bleyer

Breast Medical Oncology

Research output: Contribution to journal › Review article › peer-review

109 Scopus citations

Abstract

Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.

Original language	English (US)
Article number	e27397
Journal	Pediatric Blood and Cancer
Volume	65
Issue number	12
DOIs	https://doi.org/10.1002/pbc.27397
State	Published - Dec 2018

Keywords

age
breast
neoplasm
pregnancy
young adult

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1002/pbc.27397

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title = "Breast cancer in adolescents and young adults",

abstract = "Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.",

keywords = "age, breast, neoplasm, pregnancy, young adult",

author = "Johnson, {Rebecca H.} and Anders, {Carey K.} and Litton, {Jennifer K.} and Ruddy, {Kathryn J.} and Archie Bleyer",

note = "Funding Information: This publication was made possible by support for K.J.R. from CTSA Grant Number KL2 TR002379 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH). Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NIH. Publisher Copyright: {\textcopyright} 2018 Wiley Periodicals, Inc.",

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volume = "65",

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AU - Anders, Carey K.

AU - Litton, Jennifer K.

AU - Ruddy, Kathryn J.

AU - Bleyer, Archie

N1 - Funding Information: This publication was made possible by support for K.J.R. from CTSA Grant Number KL2 TR002379 from the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH). Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NIH. Publisher Copyright: © 2018 Wiley Periodicals, Inc.

PY - 2018/12

Y1 - 2018/12

N2 - Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.

AB - Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.

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KW - neoplasm

KW - pregnancy

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Breast cancer in adolescents and young adults

Abstract

Keywords

ASJC Scopus subject areas

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