Breast Implant-Associated Anaplastic Large Cell Lymphoma with Bone Marrow Involvement

Sanam Loghavi; L. Jeffrey Medeiros; Sanaz Javadi; Pei Lin; Joseph D. Khoury; Loretta Nastoupil; Kelly K. Hunt; Mark W. Clemens; Roberto N. Miranda

doi:10.1093/asj/sjy097

Breast Implant-Associated Anaplastic Large Cell Lymphoma with Bone Marrow Involvement

Sanam Loghavi, L. Jeffrey Medeiros, Sanaz Javadi, Pei Lin, Joseph D. Khoury, Loretta Nastoupil, Kelly K. Hunt, Mark W. Clemens, Roberto N. Miranda

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

We report a unique case of breast implant-associated anaplastic large cell lymphoma (BI-ALCL) with progressive systemic dissemination with extensive bone and bone marrow involvement. This case expands the clinical and pathologic spectrum of BI-ALCL and shows that although typically localized, BI-ALCL may present with disseminated disease with multiorgan involvement including bone and bone marrow. Disseminated BI- ALCL should be considered in the differential diagnosis of systemic ALCL. Unlike patients with localized disease, patients with disseminated BI-ALCL may benefit from systemic chemotherapy or immunotherapy. Level of Evidence: 5

Original language	English (US)
Pages (from-to)	NP92-NP96
Journal	Aesthetic surgery journal
Volume	38
Issue number	7
DOIs	https://doi.org/10.1093/asj/sjy097
State	Published - Jun 13 2018

ASJC Scopus subject areas

Surgery

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title = "Breast Implant-Associated Anaplastic Large Cell Lymphoma with Bone Marrow Involvement",

abstract = "We report a unique case of breast implant-associated anaplastic large cell lymphoma (BI-ALCL) with progressive systemic dissemination with extensive bone and bone marrow involvement. This case expands the clinical and pathologic spectrum of BI-ALCL and shows that although typically localized, BI-ALCL may present with disseminated disease with multiorgan involvement including bone and bone marrow. Disseminated BI- ALCL should be considered in the differential diagnosis of systemic ALCL. Unlike patients with localized disease, patients with disseminated BI-ALCL may benefit from systemic chemotherapy or immunotherapy. Level of Evidence: 5",

author = "Sanam Loghavi and Medeiros, {L. Jeffrey} and Sanaz Javadi and Pei Lin and Khoury, {Joseph D.} and Loretta Nastoupil and Hunt, {Kelly K.} and Clemens, {Mark W.} and Miranda, {Roberto N.}",

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T1 - Breast Implant-Associated Anaplastic Large Cell Lymphoma with Bone Marrow Involvement

AU - Loghavi, Sanam

AU - Medeiros, L. Jeffrey

AU - Javadi, Sanaz

AU - Lin, Pei

AU - Khoury, Joseph D.

AU - Nastoupil, Loretta

AU - Hunt, Kelly K.

AU - Clemens, Mark W.

AU - Miranda, Roberto N.

PY - 2018/6/13

Y1 - 2018/6/13

N2 - We report a unique case of breast implant-associated anaplastic large cell lymphoma (BI-ALCL) with progressive systemic dissemination with extensive bone and bone marrow involvement. This case expands the clinical and pathologic spectrum of BI-ALCL and shows that although typically localized, BI-ALCL may present with disseminated disease with multiorgan involvement including bone and bone marrow. Disseminated BI- ALCL should be considered in the differential diagnosis of systemic ALCL. Unlike patients with localized disease, patients with disseminated BI-ALCL may benefit from systemic chemotherapy or immunotherapy. Level of Evidence: 5

AB - We report a unique case of breast implant-associated anaplastic large cell lymphoma (BI-ALCL) with progressive systemic dissemination with extensive bone and bone marrow involvement. This case expands the clinical and pathologic spectrum of BI-ALCL and shows that although typically localized, BI-ALCL may present with disseminated disease with multiorgan involvement including bone and bone marrow. Disseminated BI- ALCL should be considered in the differential diagnosis of systemic ALCL. Unlike patients with localized disease, patients with disseminated BI-ALCL may benefit from systemic chemotherapy or immunotherapy. Level of Evidence: 5

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JO - Aesthetic surgery journal

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ER -

Breast Implant-Associated Anaplastic Large Cell Lymphoma with Bone Marrow Involvement

Abstract

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