Abstract
We conducted a double-blind pilot study involving 11 alcohol- and nicotine-dependent patients randomized to receive either bupropion or placebo. Four of six patients on bupropion and one of five patients on placebo were abstinent from smoking at the end of medication phase. Those in the bupropion group reported significantly less craving (p < .02) and less exposure to cigarette smoke over time (expired carbon monoxide; p < .01). There were no serious adverse events and no main effects of medication group on either per subject or total number of adverse events. All those who completed treatment remained abstinent from alcohol.
Original language | English (US) |
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Pages (from-to) | 487-490 |
Number of pages | 4 |
Journal | American Journal of Drug and Alcohol Abuse |
Volume | 37 |
Issue number | 6 |
DOIs | |
State | Published - Nov 2011 |
Keywords
- alcohol dependence
- bupropion
- smoking cessation
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Clinical Psychology
- Psychiatry and Mental health