Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group

Amjad Samara; Jordan Nepute; Hsiang Chih Lu; Richard J. Perrin; Rami W. Eldaya

doi:10.1016/j.radcr.2019.09.009

Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group

Amjad Samara
, Jordan Nepute
, Hsiang Chih Lu
, Richard J. Perrin
, Rami W. Eldaya

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by neoplastic proliferation of Langerhans-type dendritic cells. LCH is most frequently encountered in the pediatric populations, and involvement of the skeletal system is a common manifestation. Herein, we report a case of LCH presented as an isolated skull lesion in a 66-year-old patient. This presentation has never been reported in the literature at this advanced age and suggests that, despite being exceptionally rare, clinicians should consider LCH in the differential diagnosis of skull lesions in the elderly with classical radiological appearance.

Original language	English (US)
Pages (from-to)	1478-1482
Number of pages	5
Journal	Radiology Case Reports
Volume	14
Issue number	12
DOIs	https://doi.org/10.1016/j.radcr.2019.09.009
State	Published - Dec 2019
Externally published	Yes

Keywords

Elderly patient
Langerhans Cell Histiocytosis
Skull lesion

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.radcr.2019.09.009

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title = "Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group",

abstract = "Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by neoplastic proliferation of Langerhans-type dendritic cells. LCH is most frequently encountered in the pediatric populations, and involvement of the skeletal system is a common manifestation. Herein, we report a case of LCH presented as an isolated skull lesion in a 66-year-old patient. This presentation has never been reported in the literature at this advanced age and suggests that, despite being exceptionally rare, clinicians should consider LCH in the differential diagnosis of skull lesions in the elderly with classical radiological appearance.",

keywords = "Elderly patient, Langerhans Cell Histiocytosis, Skull lesion",

author = "Amjad Samara and Jordan Nepute and Lu, \{Hsiang Chih\} and Perrin, \{Richard J.\} and Eldaya, \{Rami W.\}",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2019",

month = dec,

doi = "10.1016/j.radcr.2019.09.009",

language = "English (US)",

volume = "14",

pages = "1478--1482",

journal = "Radiology Case Reports",

issn = "1930-0433",

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TY - JOUR

T1 - Calvarial Langerhans cell histiocytosis in an Adult

T2 - Typical imaging findings in an atypical age group

AU - Samara, Amjad

AU - Nepute, Jordan

AU - Lu, Hsiang Chih

AU - Perrin, Richard J.

AU - Eldaya, Rami W.

PY - 2019/12

Y1 - 2019/12

N2 - Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by neoplastic proliferation of Langerhans-type dendritic cells. LCH is most frequently encountered in the pediatric populations, and involvement of the skeletal system is a common manifestation. Herein, we report a case of LCH presented as an isolated skull lesion in a 66-year-old patient. This presentation has never been reported in the literature at this advanced age and suggests that, despite being exceptionally rare, clinicians should consider LCH in the differential diagnosis of skull lesions in the elderly with classical radiological appearance.

AB - Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by neoplastic proliferation of Langerhans-type dendritic cells. LCH is most frequently encountered in the pediatric populations, and involvement of the skeletal system is a common manifestation. Herein, we report a case of LCH presented as an isolated skull lesion in a 66-year-old patient. This presentation has never been reported in the literature at this advanced age and suggests that, despite being exceptionally rare, clinicians should consider LCH in the differential diagnosis of skull lesions in the elderly with classical radiological appearance.

KW - Elderly patient

KW - Langerhans Cell Histiocytosis

KW - Skull lesion

UR - https://www.scopus.com/pages/publications/85072925112

UR - https://www.scopus.com/pages/publications/85072925112#tab=citedBy

U2 - 10.1016/j.radcr.2019.09.009

DO - 10.1016/j.radcr.2019.09.009

M3 - Article

C2 - 31641396

AN - SCOPUS:85072925112

SN - 1930-0433

VL - 14

SP - 1478

EP - 1482

JO - Radiology Case Reports

JF - Radiology Case Reports

IS - 12

ER -

Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group

Abstract

Keywords

ASJC Scopus subject areas

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