Cancer biology: Gone but not forgotten

Norman E. Sharpless; Ronald A. DePinho

doi:10.1038/nature05567

Cancer biology: Gone but not forgotten

Norman E. Sharpless, Ronald A. DePinho

Research output: Contribution to journal › Short survey › peer-review

30 Scopus citations

Abstract

The p53 tumour-suppressor protein is a cell's principal guardian against cancer. Most cancers eliminate p53 - but it seems that its pathway remains intact, so resurrecting it might provide a cancer therapy.

Original language	English (US)
Pages (from-to)	606-607
Number of pages	2
Journal	Nature
Volume	445
Issue number	7128
DOIs	https://doi.org/10.1038/nature05567
State	Published - Feb 8 2007
Externally published	Yes

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title = "Cancer biology: Gone but not forgotten",

abstract = "The p53 tumour-suppressor protein is a cell's principal guardian against cancer. Most cancers eliminate p53 - but it seems that its pathway remains intact, so resurrecting it might provide a cancer therapy.",

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AU - DePinho, Ronald A.

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Cancer biology: Gone but not forgotten

Abstract

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