Cancer biomarkers - Current perspectives

Anant Narayan Bhatt, Rohit Mathur, Abdullah Farooque, Amit Verma, B. S. Dwarakanath

Research output: Contribution to journalReview article

119 Citations (Scopus)

Abstract

In the recent years, knowledge about cancer biomarkers has increased tremendously providing great opportunities for improving the management of cancer patients by enhancing the effciency of detection and effcacy of treatment. Recent technological advancement has enabled the examination of many potential biomarkers and renewed interest in developing new biomarkers. Biomarkers of cancer could include a broad range of biochemical entities, such as nucleic acids, proteins, sugars, lipids, and small metabolites, cytogenetic and cytokinetic parameters as well as whole tumour cells found in the body fuid. A comprehensive understanding of the relevance of each biomarker will be very important not only for diagnosing the disease reliably, but also help in the choice of multiple therapeutic alternatives currently available that is likely to beneft the patients. This review provides a brief account on various biomarkers for diagnosis, prognosis and therapeutic purposes, which include markers already in clinical practice as well as various upcoming biomarkers.

Original languageEnglish (US)
Pages (from-to)129-149
Number of pages21
JournalIndian Journal of Medical Research
Volume132
Issue number8
StatePublished - Sep 2 2010

Fingerprint

Biomarkers
Tumor Biomarkers
Metabolites
Cytogenetics
Sugars
Nucleic Acids
Tumors
Neoplasms
Therapeutics
Cells
Lipids
Proteins

Keywords

  • Biomarkers
  • Cancer
  • Cancer therapy
  • Diagnosis
  • Glycolysis
  • Molecular targets
  • Pin 1
  • Prognosis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Bhatt, A. N., Mathur, R., Farooque, A., Verma, A., & Dwarakanath, B. S. (2010). Cancer biomarkers - Current perspectives. Indian Journal of Medical Research, 132(8), 129-149.

Cancer biomarkers - Current perspectives. / Bhatt, Anant Narayan; Mathur, Rohit; Farooque, Abdullah; Verma, Amit; Dwarakanath, B. S.

In: Indian Journal of Medical Research, Vol. 132, No. 8, 02.09.2010, p. 129-149.

Research output: Contribution to journalReview article

Bhatt, AN, Mathur, R, Farooque, A, Verma, A & Dwarakanath, BS 2010, 'Cancer biomarkers - Current perspectives' Indian Journal of Medical Research, vol. 132, no. 8, pp. 129-149.
Bhatt AN, Mathur R, Farooque A, Verma A, Dwarakanath BS. Cancer biomarkers - Current perspectives. Indian Journal of Medical Research. 2010 Sep 2;132(8):129-149.
Bhatt, Anant Narayan ; Mathur, Rohit ; Farooque, Abdullah ; Verma, Amit ; Dwarakanath, B. S. / Cancer biomarkers - Current perspectives. In: Indian Journal of Medical Research. 2010 ; Vol. 132, No. 8. pp. 129-149.
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