Abstract
Precision medicine requires appropriate application of genomics in clinical practice. In cancer, we have witnessed practice-changing examples of how genomic knowledge is translated into more tailored and effective therapies. The next opportunity is to embed cancer genomics in clinical context so that patient-centric longitudinal clinical, genomic, and molecular phenotypes can be compiled for adaptive learning between precision medicine research and clinical care with the goal of accelerating clinically-actionable discoveries. We describe here an adaptive learning platform, APOLLO™ (adaptive patient-oriented longitudinal learning and optimization) designed to integrate genomic research in the context of, but not in the path of, routine and investigational clinical care for purposes of enabling data-driven discovery across disciplines such that every patient can contribute to and potentially benefit from research discoveries.
Original language | English (US) |
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Pages (from-to) | 36-43 |
Number of pages | 8 |
Journal | Trends in Cancer |
Volume | 1 |
Issue number | 1 |
DOIs | |
State | Published - Sep 1 2015 |
Keywords
- N-of-ALL
- adaptive learning
- data-driven science and care
- longitudinal genomics-phenomics profiling
- patient-oriented genomic research
ASJC Scopus subject areas
- Oncology
- Cancer Research