Cancer genomics: one cell at a time

Nicholas E. Navin

doi:10.1186/s13059-014-0452-9

Cancer genomics: one cell at a time

Nicholas E. Navin

Research output: Contribution to journal › Review article › peer-review

227 Scopus citations

Abstract

The study of single cancer cells has transformed from qualitative microscopic images to quantitative genomic datasets. This paradigm shift has been fueled by the development of single-cell sequencing technologies, which provide a powerful new approach to study complex biological processes in human cancers.

Original language	English (US)
Article number	452
Pages (from-to)	452
Number of pages	1
Journal	Genome biology
Volume	15
Issue number	8
DOIs	https://doi.org/10.1186/s13059-014-0452-9
State	Published - 2014

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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title = "Cancer genomics: one cell at a time",

abstract = "The study of single cancer cells has transformed from qualitative microscopic images to quantitative genomic datasets. This paradigm shift has been fueled by the development of single-cell sequencing technologies, which provide a powerful new approach to study complex biological processes in human cancers. ",

author = "Navin, {Nicholas E.}",

note = "Funding Information: NN is a Nadia{\textquoteright}s Gift Foundation Damon Runyon-Rachleff Innovator (DRR-25-13). This work is supported by grants to NN from NIH (R21CA174397-01) and NCI (1RO1CA169244-01). NN is also supported by the Center for Genetics & Genomics, TC Hsu Foundation and the Alice-Reynolds Kleberg Foundation.",

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T2 - one cell at a time

AU - Navin, Nicholas E.

N1 - Funding Information: NN is a Nadia’s Gift Foundation Damon Runyon-Rachleff Innovator (DRR-25-13). This work is supported by grants to NN from NIH (R21CA174397-01) and NCI (1RO1CA169244-01). NN is also supported by the Center for Genetics & Genomics, TC Hsu Foundation and the Alice-Reynolds Kleberg Foundation.

PY - 2014

Y1 - 2014

N2 - The study of single cancer cells has transformed from qualitative microscopic images to quantitative genomic datasets. This paradigm shift has been fueled by the development of single-cell sequencing technologies, which provide a powerful new approach to study complex biological processes in human cancers.

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Cancer genomics: one cell at a time

Abstract

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