Cancer signaling: When phosphorylation meets methylation

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The propagation of kinase-mediated phosphorylation signals is central to the oncogenic activity of the RAS-MAPK pathway in human cancers. A recent study shows that protein lysine methylation controls the phosphorylation status of a key component of the RAS-MAPK pathway to enable oncogenic KRAS in cancer progression.

Original languageEnglish (US)
Pages (from-to)1282-1283
Number of pages2
JournalCell research
Volume24
Issue number11
DOIs
StatePublished - Nov 5 2014

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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