Cancers in France in 2015 attributable to occupational exposures

Claire Marant Micallef, Kevin D. Shield, Jérôme Vignat, Isabelle Baldi, Barbara Charbotel, Béatrice Fervers, Anabelle Gilg Soit Ilg, Pascal Guénel, Ann Olsson, Lesley Rushton, Sally J. Hutchings, Enora Cléro, Dominique Laurier, Pascale Scanff, Freddie Ian Bray, Kurt Straif, Isabelle Soerjomataram

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Recent and comprehensive estimates for the number of new cancer cases in France attributable to occupational exposures are lacking. Objectives: To estimate the number of new cancer cases attributable to occupational exposures, using a newly developed methodology and the most recent data, for a comprehensive set of occupational carcinogens in France in 2015. Methods: Surveys among employees, the national labor force data, a cohort of agricultural workers, national monitoring of workers exposed to ionizing radiation and job-exposure matrix in France were used. The number and proportion of new cancer cases attributable to established occupational carcinogens (Group 1) was estimated using estimation of lifetime exposure and risk estimates from cohort studies. Cancer data were obtained from the French Cancer Registries Network. Results: In France in 2015, an estimated 7905 new cancer cases, 7336 among men and 569 among women, were attributable to occupational exposures, representing 2.3% of all new cancer cases (3.9% and 0.4% among men and women respectively). Among men and women, lung cancer was impacted the most, followed by mesothelioma and bladder cancer in men, and by mesothelioma and ovary in women. These cancers contributed to 89% of the total cancers attributable to occupational carcinogens in men, and to 80% in women. The main contributing occupational agent was asbestos among men (45%) and women (60%). Conclusions: Currently, occupational exposures contribute to a substantial burden of cancer in France. Enhanced monitoring and implementation of protective labor policies could potentially prevent a large proportion of these cancers.

Original languageEnglish (US)
Pages (from-to)22-29
Number of pages8
JournalInternational Journal of Hygiene and Environmental Health
Volume222
Issue number1
DOIs
StatePublished - Jan 1 2019

Fingerprint

Occupational Exposure
France
Neoplasms
Carcinogens
Mesothelioma
Occupational Groups
Asbestos
Ionizing Radiation
Urinary Bladder Neoplasms
Registries
Ovary
Lung Neoplasms
Cohort Studies

Keywords

  • Cancer
  • Carcinogen
  • Comparative risk assessment/attributable fractions
  • Occupation
  • Risk

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Marant Micallef, C., Shield, K. D., Vignat, J., Baldi, I., Charbotel, B., Fervers, B., ... Soerjomataram, I. (2019). Cancers in France in 2015 attributable to occupational exposures. International Journal of Hygiene and Environmental Health, 222(1), 22-29. https://doi.org/10.1016/j.ijheh.2018.07.015

Cancers in France in 2015 attributable to occupational exposures. / Marant Micallef, Claire; Shield, Kevin D.; Vignat, Jérôme; Baldi, Isabelle; Charbotel, Barbara; Fervers, Béatrice; Gilg Soit Ilg, Anabelle; Guénel, Pascal; Olsson, Ann; Rushton, Lesley; Hutchings, Sally J.; Cléro, Enora; Laurier, Dominique; Scanff, Pascale; Bray, Freddie Ian; Straif, Kurt; Soerjomataram, Isabelle.

In: International Journal of Hygiene and Environmental Health, Vol. 222, No. 1, 01.01.2019, p. 22-29.

Research output: Contribution to journalArticle

Marant Micallef, C, Shield, KD, Vignat, J, Baldi, I, Charbotel, B, Fervers, B, Gilg Soit Ilg, A, Guénel, P, Olsson, A, Rushton, L, Hutchings, SJ, Cléro, E, Laurier, D, Scanff, P, Bray, FI, Straif, K & Soerjomataram, I 2019, 'Cancers in France in 2015 attributable to occupational exposures' International Journal of Hygiene and Environmental Health, vol. 222, no. 1, pp. 22-29. https://doi.org/10.1016/j.ijheh.2018.07.015
Marant Micallef, Claire ; Shield, Kevin D. ; Vignat, Jérôme ; Baldi, Isabelle ; Charbotel, Barbara ; Fervers, Béatrice ; Gilg Soit Ilg, Anabelle ; Guénel, Pascal ; Olsson, Ann ; Rushton, Lesley ; Hutchings, Sally J. ; Cléro, Enora ; Laurier, Dominique ; Scanff, Pascale ; Bray, Freddie Ian ; Straif, Kurt ; Soerjomataram, Isabelle. / Cancers in France in 2015 attributable to occupational exposures. In: International Journal of Hygiene and Environmental Health. 2019 ; Vol. 222, No. 1. pp. 22-29.
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abstract = "Background: Recent and comprehensive estimates for the number of new cancer cases in France attributable to occupational exposures are lacking. Objectives: To estimate the number of new cancer cases attributable to occupational exposures, using a newly developed methodology and the most recent data, for a comprehensive set of occupational carcinogens in France in 2015. Methods: Surveys among employees, the national labor force data, a cohort of agricultural workers, national monitoring of workers exposed to ionizing radiation and job-exposure matrix in France were used. The number and proportion of new cancer cases attributable to established occupational carcinogens (Group 1) was estimated using estimation of lifetime exposure and risk estimates from cohort studies. Cancer data were obtained from the French Cancer Registries Network. Results: In France in 2015, an estimated 7905 new cancer cases, 7336 among men and 569 among women, were attributable to occupational exposures, representing 2.3{\%} of all new cancer cases (3.9{\%} and 0.4{\%} among men and women respectively). Among men and women, lung cancer was impacted the most, followed by mesothelioma and bladder cancer in men, and by mesothelioma and ovary in women. These cancers contributed to 89{\%} of the total cancers attributable to occupational carcinogens in men, and to 80{\%} in women. The main contributing occupational agent was asbestos among men (45{\%}) and women (60{\%}). Conclusions: Currently, occupational exposures contribute to a substantial burden of cancer in France. Enhanced monitoring and implementation of protective labor policies could potentially prevent a large proportion of these cancers.",
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AU - Marant Micallef, Claire

AU - Shield, Kevin D.

AU - Vignat, Jérôme

AU - Baldi, Isabelle

AU - Charbotel, Barbara

AU - Fervers, Béatrice

AU - Gilg Soit Ilg, Anabelle

AU - Guénel, Pascal

AU - Olsson, Ann

AU - Rushton, Lesley

AU - Hutchings, Sally J.

AU - Cléro, Enora

AU - Laurier, Dominique

AU - Scanff, Pascale

AU - Bray, Freddie Ian

AU - Straif, Kurt

AU - Soerjomataram, Isabelle

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N2 - Background: Recent and comprehensive estimates for the number of new cancer cases in France attributable to occupational exposures are lacking. Objectives: To estimate the number of new cancer cases attributable to occupational exposures, using a newly developed methodology and the most recent data, for a comprehensive set of occupational carcinogens in France in 2015. Methods: Surveys among employees, the national labor force data, a cohort of agricultural workers, national monitoring of workers exposed to ionizing radiation and job-exposure matrix in France were used. The number and proportion of new cancer cases attributable to established occupational carcinogens (Group 1) was estimated using estimation of lifetime exposure and risk estimates from cohort studies. Cancer data were obtained from the French Cancer Registries Network. Results: In France in 2015, an estimated 7905 new cancer cases, 7336 among men and 569 among women, were attributable to occupational exposures, representing 2.3% of all new cancer cases (3.9% and 0.4% among men and women respectively). Among men and women, lung cancer was impacted the most, followed by mesothelioma and bladder cancer in men, and by mesothelioma and ovary in women. These cancers contributed to 89% of the total cancers attributable to occupational carcinogens in men, and to 80% in women. The main contributing occupational agent was asbestos among men (45%) and women (60%). Conclusions: Currently, occupational exposures contribute to a substantial burden of cancer in France. Enhanced monitoring and implementation of protective labor policies could potentially prevent a large proportion of these cancers.

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