CanSAR: Update to the cancer translational research and drug discovery knowledgebase

Elizabeth A. Coker, Costas Mitsopoulos, Joesph E. Tym, Angeliki Komianou, Christos Kannas, Patrizio Di Micco, Eloy Villasclaras Fernandez, Bugra Ozer, Albert A. Antolin, Paul Workman, Bissan Al-Lazikani

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and unique, comprehensive and orthogonal 'druggability' assessments. canSAR is widely used internationally by academia and industry. Here we describe major enhancements to canSAR including new and expanded data. We also describe the first components of canSARblack-an advanced, responsive, multi-device compatible redesign of canSAR with a question-led interface.

Original languageEnglish (US)
Pages (from-to)D917-D922
JournalNucleic acids research
Volume47
Issue numberD1
DOIs
StatePublished - Jan 8 2019
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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