Case report: a fatal case of Aspergillus felis infection in an immunocompetent host

Jill Parkes-Smith; Michelle J. Bauer; Haakon Bergh; Anthony Eidan; Brian M. Forde; John Hilton; Timothy J. Kidd; Campbell Schmidt; Adam G. Stewart; Patrick N.A. Harris

doi:10.1099/acmi.0.000453

Case report: a fatal case of Aspergillus felis infection in an immunocompetent host

Jill Parkes-Smith
, Michelle J. Bauer
, Haakon Bergh
, Anthony Eidan
, Brian M. Forde
, John Hilton
, Timothy J. Kidd
, Campbell Schmidt
, Adam G. Stewart
, Patrick N.A. Harris

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been documented, all of which had significant immunosuppression. This is the first human death due to A. felis described in an immunocompetent host.

Original language	English (US)
Article number	000453
Journal	Access Microbiology
Volume	4
Issue number	11
DOIs	https://doi.org/10.1099/acmi.0.000453
State	Published - 2022
Externally published	Yes

Keywords

aspergillosis
Aspergillus felis
cryptic Aspergillus species

ASJC Scopus subject areas

Microbiology
Microbiology (medical)

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10.1099/acmi.0.000453

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title = "Case report: a fatal case of Aspergillus felis infection in an immunocompetent host",

abstract = "We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been documented, all of which had significant immunosuppression. This is the first human death due to A. felis described in an immunocompetent host.",

keywords = "aspergillosis, Aspergillus felis, cryptic Aspergillus species",

author = "Jill Parkes-Smith and Bauer, \{Michelle J.\} and Haakon Bergh and Anthony Eidan and Forde, \{Brian M.\} and John Hilton and Kidd, \{Timothy J.\} and Campbell Schmidt and Stewart, \{Adam G.\} and Harris, \{Patrick N.A.\}",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors.",

year = "2022",

doi = "10.1099/acmi.0.000453",

language = "English (US)",

volume = "4",

journal = "Access Microbiology",

issn = "2516-8290",

publisher = "Microbiology Society",

number = "11",

}

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T2 - a fatal case of Aspergillus felis infection in an immunocompetent host

AU - Parkes-Smith, Jill

AU - Bauer, Michelle J.

AU - Bergh, Haakon

AU - Eidan, Anthony

AU - Forde, Brian M.

AU - Hilton, John

AU - Kidd, Timothy J.

AU - Schmidt, Campbell

AU - Stewart, Adam G.

AU - Harris, Patrick N.A.

PY - 2022

Y1 - 2022

N2 - We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been documented, all of which had significant immunosuppression. This is the first human death due to A. felis described in an immunocompetent host.

AB - We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been documented, all of which had significant immunosuppression. This is the first human death due to A. felis described in an immunocompetent host.

KW - aspergillosis

KW - Aspergillus felis

KW - cryptic Aspergillus species

UR - https://www.scopus.com/pages/publications/85194053831

UR - https://www.scopus.com/pages/publications/85194053831#tab=citedBy

U2 - 10.1099/acmi.0.000453

DO - 10.1099/acmi.0.000453

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AN - SCOPUS:85194053831

SN - 2516-8290

VL - 4

JO - Access Microbiology

JF - Access Microbiology

IS - 11

M1 - 000453

ER -

Case report: a fatal case of Aspergillus felis infection in an immunocompetent host

Abstract

Keywords

ASJC Scopus subject areas

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