Challenges Associated with Reoperation in Patients with Glioma

Rasheed Zakaria, Jeffrey S. Weinberg

Research output: Contribution to journalReview articlepeer-review


Reoperation for glioma is increasingly common but there is neither firm agreement on the indications nor unequivocally proven benefit from clinical trials. Patient and tumor factors should be considered when offering reoperation and a clear surgical goal set. Reoperation is challenging because of placement of previous incisions, wound devascularization by preceding radiotherapy and/or chemotherapy, chronic steroid use, the need for further adjuvant therapy, and adherent and defective dura. This article reviews indications, challenges, and recommendations for repeat surgery in the patient with glioma.

Original languageEnglish (US)
Pages (from-to)129-135
Number of pages7
JournalNeurosurgery clinics of North America
Issue number1
StatePublished - Jan 2021


  • Glioblastoma
  • Glioma
  • Progression
  • Recurrence
  • Redo surgery
  • Reoperation

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Challenges Associated with Reoperation in Patients with Glioma'. Together they form a unique fingerprint.

Cite this