TY - JOUR
T1 - Challenges in Interpretation of Staging PET/CT in Thoracic Malignancies
AU - Shroff, Girish S.
AU - Carter, Brett W.
AU - Viswanathan, Chitra
AU - Benveniste, Marcelo F.
AU - Wu, Carol C.
AU - Marom, Edith M.
AU - Mawlawi, Osama R.
AU - Truong, Mylene T.
PY - 2017/7
Y1 - 2017/7
N2 - 18F-fluorodeoxryglucose (18F-FDG) PET/CT imaging is routinely performed in the evaluation of patients with known or suspected thoracic malignancy. Indications for its use include staging of malignancy, assessment of response to therapy, evaluation of suspected disease recurrence, and evaluation of a solitary pulmonary nodule. In this article, we will discuss specific technical artifacts and also review potential pitfalls in the interpretation of PET/CT in thoracic malignancies including normal variations in physiologic uptake of FDG, benign conditions (such as infection, inflammation, posttreatment changes, and iatrogenic factors) that can result in increased FDG uptake, and malignancies that demonstrate scarce to no FDG uptake.
AB - 18F-fluorodeoxryglucose (18F-FDG) PET/CT imaging is routinely performed in the evaluation of patients with known or suspected thoracic malignancy. Indications for its use include staging of malignancy, assessment of response to therapy, evaluation of suspected disease recurrence, and evaluation of a solitary pulmonary nodule. In this article, we will discuss specific technical artifacts and also review potential pitfalls in the interpretation of PET/CT in thoracic malignancies including normal variations in physiologic uptake of FDG, benign conditions (such as infection, inflammation, posttreatment changes, and iatrogenic factors) that can result in increased FDG uptake, and malignancies that demonstrate scarce to no FDG uptake.
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U2 - 10.1067/j.cpradiol.2016.11.012
DO - 10.1067/j.cpradiol.2016.11.012
M3 - Review article
C2 - 28159371
AN - SCOPUS:85011117108
SN - 0363-0188
VL - 46
SP - 330
EP - 341
JO - Current Problems in Diagnostic Radiology
JF - Current Problems in Diagnostic Radiology
IS - 4
ER -