@inbook{e23d49412f0c4f00bd3e277c1f74f72a,
title = "CHAPTER 2: Protein-Protein Interaction Networks in Human Disease",
abstract = "Protein-protein interactions (PPIs) are a foundational life process. Much work over the past few decades has uncovered countless roles that protein-protein interactions play in both health and disease. Most of this work examined the interactions between only two proteins at a time. Recently, however, there has been a surge of research examining entire networks of PPIs in disease conditions. This chapter covers the basic principles of PPI network analysis, methodologies commonly employed to generate PPI networks, and the role that PPI network analysis plays in diverse diseases, including cancer, diabetes, and neurodegenerative diseases, among others.",
author = "Dunn, {Brandon S.} and Sharad Awasthi and Song Yi and Nidhi Sahni",
note = "Funding Information: n.S. is a CPrIt Scholar in Cancer research with funding from the Cancer Prevention and research Institute of texas (CPrIt) new Investigator Grant rr160021. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2021.",
year = "2021",
doi = "10.1039/9781788016544-00025",
language = "English (US)",
series = "RSC Drug Discovery Series",
publisher = "Royal Society of Chemistry",
number = "78",
pages = "25--48",
editor = "Siddhartha Roy and Haian Fu",
booktitle = "Protein Degradation with New Chemical Modalities",
edition = "78",
}