Characterization of adipose-derived stem cells: An update

Alexander M. Bailey; Sahil Kapur; Adam J. Katz

doi:10.2174/157488810791268555

Characterization of adipose-derived stem cells: An update

Alexander M. Bailey, Sahil Kapur, Adam J. Katz

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.

Original language	English (US)
Pages (from-to)	95-102
Number of pages	8
Journal	Current Stem Cell Research and Therapy
Volume	5
Issue number	2
DOIs	https://doi.org/10.2174/157488810791268555
State	Published - 2010
Externally published	Yes

Keywords

Adipose-derived stem cell
Characterization
Donor variability
Expansion
Isolation
Stromal cell

ASJC Scopus subject areas

Medicine (miscellaneous)

Access to Document

10.2174/157488810791268555

Cite this

@article{68296acf94df4e7a8356b0938c63f01a,

title = "Characterization of adipose-derived stem cells: An update",

abstract = "Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.",

keywords = "Adipose-derived stem cell, Characterization, Donor variability, Expansion, Isolation, Stromal cell",

author = "Bailey, {Alexander M.} and Sahil Kapur and Katz, {Adam J.}",

year = "2010",

doi = "10.2174/157488810791268555",

language = "English (US)",

volume = "5",

pages = "95--102",

journal = "Current Stem Cell Research and Therapy",

issn = "1574-888X",

publisher = "Bentham Science Publishers B.V.",

number = "2",

}

TY - JOUR

T1 - Characterization of adipose-derived stem cells

T2 - An update

AU - Bailey, Alexander M.

AU - Kapur, Sahil

AU - Katz, Adam J.

PY - 2010

Y1 - 2010

N2 - Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.

AB - Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.

KW - Adipose-derived stem cell

KW - Characterization

KW - Donor variability

KW - Expansion

KW - Isolation

KW - Stromal cell

UR - http://www.scopus.com/inward/record.url?scp=77954082044&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954082044&partnerID=8YFLogxK

U2 - 10.2174/157488810791268555

DO - 10.2174/157488810791268555

M3 - Article

C2 - 19941461

AN - SCOPUS:77954082044

SN - 1574-888X

VL - 5

SP - 95

EP - 102

JO - Current Stem Cell Research and Therapy

JF - Current Stem Cell Research and Therapy

IS - 2

ER -

Characterization of adipose-derived stem cells: An update

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this